Endocrine Abstracts (2012) 28 P14

Unusual presentation of idiopathic hypoparathyrodism with hyper-CK-emia

Shujah Dar, Anjaneya Bapat, Vidya Jahagirdar & Cheriyan Geevarghese


Medicine, Queens Hospital Burton, Burton-On-Trent, United Kingdom.


We report a case of a 51 year-old gentleman with increased serum creatine kinase (CK) due to hypocalcaemic tetany caused by idiopathic hypoparathyrodism. Raised CK (1738 u/L) was incidentally noted in this patient by his GP. He had ongoing symptoms of hypocalcaemia with intermittent tetanic spasms in his hands and scalp and easy fatigability for 2 years. His examination showed normal stature, no evidence of myopathy with normal deep tendon reflexes, Trousseau’s sign was present while Chvostek’s sign was absent. His electrocardiogram (ECG) revealed a slightly prolonged QTc of 497 milliseconds. His laboratory findings showed hypocalcaemia (1.08 mmol/L) and hyperphosphataemia (2.57 mmol/L) with low PTH (5 pg/ml) while his vitamin D levels were satisfactory. After supplementation with alfacalcidol and calcium carbonate his hypocalcaemia and hyper-CK-emia resolved and his symptoms improved. We suggested that elevation of his muscle enzymes was related to episodes of tetany he was having with his low calcium.

Declaration of interest: There is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

Funding: No specific grant from any funding agency in the public, commercial or not-for-profit sector.

Article tools

My recent searches

No recent searches.