Endocrine Abstracts (2012) 28 P237

Management of prolactinomas during pregnancy - A survey of four canadian provinces

Mussa Almalki1, Michelle Johnson1, Ehud Ur1, David Clarke2 & Syed Ali Imran2


1Division of Endocrinology and Metabolism, UBC, Vancouver, BC, Canada; 2Divisions of Neurosurgery and Endocrinology and Metabolism, Dalhousie University, Halifax, NS, Canada.


The guidelines for management of prolactinomas (PRLoma) during pregnancy are mostly based on retrospective evidence or expert opinion. We conducted a survey of four Canadian provinces (NS, NB, PEI and BC) to assess the current trends in management of PRLoma during pregnancy. A case-based electronic questionnaire was sent to all practicing endocrinologists, with 3 cases of varying severity ranging from a micro PRLoma to a large macroPRLoma compressing the optic chiasm. A total of 60 endocrinologists were identified; the response rate was 57%. Most responder (62%) were based at university hospitals of which 65% saw 1–5 cases on PRLoma each month. There was considerable diversity among specialist in regards to the management of PRLoma during pregnancy (see table-1). In Conclusion, among endocrinologists there is a considerable diversity in management of PRLoma during pregnancy indicating a need for better consensus and clearer guidelines.

Declaration of interest: There is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

Funding: No specific grant from any funding agency in the public, commercial or not-for-profit sector.

Table 1: Results are expressed as percentages of responders

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