Searchable abstracts of presentations at key conferences in endocrinology
15th International & 14th European Congress of Endocrinology
Plenary Lectures
Red wine Endocrinology
ea0029pl1 | Red wine Endocrinology | ICEECE2012
New insights into the roles of sirtuins in metabolic decline and disease of aging
Sirtuins are NAD+-dependent deacetylases that are implicated in mediating health benefits of calorie restriction and possibly exercise. We will report on novel roles of SIRT1-3 in diseases of aging and recent progress in using small molecules to activate SIRT1. Small molecule activators of SIRT1 (STACs), such as resveratrol and SRT1720, improve multiple health parameters in mice including protection from type II diabetes and hepatic steatosis. We developed an system...
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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