Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 29 | ICEECE2012 | Next issue

15th International & 14th European Congress of Endocrinology

Symposia

Circadian regulation of metabolism

ea0029s50.1 | Circadian regulation of metabolism | ICEECE2012

Basic mechanisms of circadian regulation in the brain

Oster H.

Circadian clocks regulate the adaptation of the organism to the rotation of the earth around its axis. In mammals the circadian timing system is comprised of numerous cellular oscillators throughout the brain and the body. In the hypothalamic suprachiasmatic nucleus a circadian pacemaker is synchronized to the external light/dark cycle via direct innervation along the retinohypothalamic tract. From the SCN, peripheral clocks are synchronized by neuronal, endocrine and behavior...

ea0029s50.3 | Circadian regulation of metabolism | ICEECE2012

Circadian rhythms in adipose tissue

Gimble J. , Ptitsyn A. , Floyd Z.

Circadian mechanisms regulate metabolism in adipose tissues. The genes encoding the circadian regulatory proteins oscillate over a 24 h period in human and murine adipose tissue depots,. This expression profile is entrained by photic stimuli, temporally restricted food access, and/or nuclear hormone receptor ligands, such as glucocorticoids. In mice, deletion or mutation of the circadian regulatory genes, clock and PPAR gamma coactivator 1 (PGC1), is associated with increased ...