Endocrine Abstracts (2012) 29 P372

Pituicytoma and meningeoma presenting as suprasellar tumor: case report

G. Pemovska, B. Krstevska & B. Jovanovska

University Clinical Center, Skopje, The Former Yugoslav Republic of Macedonia.

Pituicytoms is a very rare low-grade glioma of the neurohypophysis and can affect both the sellar and suprasellar regions. We describe a case of a suprasellar pituicytoma and mengioma of a patient admitted to our Clinic as a suprasellar tumor patient.

Clinical presentation: A 55-years-old man with a history of persistent headache in the right frontal area for a period of 10 years prior to the admission as well as visual disturbances and decreased libido for 1 year period prior to the admission. The hormonal profile revealed low FSH (0.368 mU/l), LH (0.1 mU/l), testosterone, cortisol (6.34 nmol/l) and PRL (19.39). Magnetic resonance imaging showed a solid homogeneously enhancing suprasellar mass 2.5 cm compressing the optic chiasm. A craniotomia pteryonal l. dex. was performed as well as a subtotal resection of the tumor. The hystopathological finding indicated meningeoma fibroblasticum. Due to the deterioration of the sight a new MRI was performed after 9 months that showed an identical finding of suprasellar macroadenoma. A recraniotomia reg, frontalis l. dex. and reextirpatio tumoris were performed and the hystopathological finding indicated pituicytoma (infundibuloma) Ki 67 <3%. After

The surgery was followed by a radiation therapy, after which the patient developed symptoms of frontal lobi, diabetes mellitus and diabetes insipidus. The patient died of a heavy adrenalin crisis.

Conclusion: Pituicytoma are rare tumors of the neurohypophysis. The clinical presentation is similar to other non-functional pituitary adenomas and imaging exams may suggest pituitary adenomas. The diagnostic is based on histopatological analysis.

Key words: Hypophysis, Pituicytoma, pituitary tumors, neurohypophyseal tumor.

Declaration of interest: The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.

Funding: This research did not receive any specific grant from any funding agency in the public, commercial or not-for-profit sector.

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