Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2013) 31 P123 | DOI: 10.1530/endoabs.31.P123

SFEBES2013 Poster Presentations Clinical practice/governance and case reports (79 abstracts)

Degree of bone mineral density improvement in patients with osteoporosis on current NICE recommended treatments: an audit

Parijat De 1 & Rachel Reed 2


1Department of Diabetes and Endocrinology, City Hospital, Birmingham, UK; 2Birmingham Medical School, Birmingham, UK.


Aims: To identify any improvements in BMD on NICE recommended treatments in patients with osteoporosis. Also to identify how many patients were taking calcium and vitamin D.

Methods: Retrospective audit of 31 patients who had a DEXA scan between June 2011 and October 2012 at Birmingham City Hospital. Patient information was gathered from electronic data base (Clinical Data Archive). Inclusion criteria was at least two DEXA scan T-scores results, one before and after at least 1 year of treatment.

Results: 63% were females, mean age 54 years, 42% were White British and mean duration of osteoporosis 4 years. Cause of osteoporosis was varied. 24/31 patients met audit standards. 70% of patients were taking Alendronic acid. 100% of the patients with osteoporosis were taking calcium and vitamin D supplements. 58% had an improvement in spine and femur T-score (mean improvement 1.2 S.D.). three patients had a deterioration DEXA T-score and treatment was changed according to NICE guidelines to Raloxifene (2) and to Strontium Ranelate (1). three patients had a deterioration in femur T-score only and four had a deterioration in the spine T-score.

Conclusions: Nearly 2/3rd of patients (58%) with osteoporosis on NICE recommended treatments experienced significant improvements in spine and femur BMD. 100% of the patients were taking calcium and vitamin D according to recommended guidelines. This audit shows that current treatment for osteoporosis is effective and most patients adhere to their drugs although compliance was difficult to ascertain from the data base. In future we plan to audit compliance and patient satisfaction prospectively.

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