Endocrine Abstracts

Research into ageing has been transformed by the discovery of single gene mutations that extend healthy lifespan in laboratory model organisms. Furthermore, the highly conserved, nutrient-sensing, insulin/IGF/TOR signalling network has proved to play a role in ageing in organisms including yeast, invertebrates and mice, and possibly also humans. This signalling network also mediates at least some of the effects of dietary restriction, which also improves health during ageing a...