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Endocrine Abstracts (2013) 32 P299 | DOI: 10.1530/endoabs.32.P299

1Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Bulent Ecevit University, Zonguldak, Turkey; 2Department of Nuclear Medicine, Faculty of Medicine, Bulent Ecevit University, Zonguldak, Turkey; 3Department of Internal Medicine, Faculty of Medicine, Bulent Ecevit University, Zonguldak, Turkey; 4Department of Gynecology and Obstetrics, Zonguldak, Turkey.


Introduction: Thyroid disorders such as subacute thyroiditis occur rarely in pregnancy. We report a recurrent case of subacute thyroiditis improved with the onset of pregnancy.

Case report: A 32-year-old Turkish women who request pregnancy and planned insemination was referred due to malaise and neck pain in the left side a week ago. She was presented with low-grade fever, fatigue, pharingitis symptoms, neck pain and extremely tenderness in the right side of thyroid about four months ago. Subacute thyroiditis was diagnosed with colour doppler sonography of thyroid showed decreased vascularise and flow in the thyroid and elevated markers of inflammation. Owing to increasing symptoms and signs, glucocorticoid therapy was given. Three months after discontinuation of steroid therapy with relief, she was admitted to the other side neck pain and tenderness during the induction of ovulation. Her symptoms, signs and inflammatory parameters were progressed. Hence, steroid therapy was given a short course to the patient on five days before insemination. It is discontinued before the day of insemination. During first month of pregnancy, the clinic situation was resolved, and improved without need for medications. Because of hypothyroidism, levothyroxine was given throughout pregnancy.

Conclusions: Subacute thyroiditis is rare and an important disorders during pregnancy. The beginning of pregnancy, physiological and immunological mechanisms may be responsible for the recovery of subacute thyroiditis.

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