The objectives of this talk are to outline how the role of the Endocrine nurse fits into clinical trials. Nurses working in clinical trials usually operate at an advanced level, delivering experience, knowledge and autonomous practice. The Endocrine research nurse is responsible for liaising with and co-ordinating the care of Endocrine patients with complex conditions into research studies. Then organising and synchronising these studies by collaborating with other members of the research team and the wider multi-disciplinary team in the management of clinical trials. Attention to the principles of good clinical practice is paramount and also excellent IT skills are required. The ability to organise own workload on a daily basis in accordance with clinical demands is essential.