Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 35 | ECE2014 | Next issue

16th European Congress of Endocrinology

Poster Presentations

Clinical case reports Thyroid/Others

ea0035p261 | Clinical case reports Thyroid/Others | ECE2014

A new mutation associated with pseudohypoparathyroidism? two case reports

Roca-Rodriguez MM , Maraver-Selfa S , Cornejo-Pareja I , Munoz-Garach A , Gomez-Perez A , Molina-Vega M , Mancha-Doblas I , Tinahones F J

We describe the clinical case of two childbearing age women with thyroid dysfunction, hypocalcemia, hyperphosphatemia, and high levels of PTH.Case 1: A 34-year-old woman with infertility for 3 years, microprolactinoma treated with low-dose dopamine agonists, autoimmune primary hypothyroidism and obesity. She had irregular menstrual cycles and fatigue. Weight 130 kg, height 155 cm, cervical acanthosis nigricans and round face. Calcium 6.6 mg/dl, phosphoro...

ea0035p262 | Clinical case reports Thyroid/Others | ECE2014

Prevalence of thyroid abnormalities among psoriatic patients

Chiriac Anca , Chiriac Anca E , Pinteala Tudor , Foia Liliana

Introduction: Psoriasis is not only a skin disease, is a chronic inflammatory disease associated with serious comorbidities: psoriatic arthritis, metabolic syndrome (obesity, dyslipidemia and insulin resistance), Crohn’s disease, depression, ocular problems, cardio-vascular diseases (myocardial infarction), cancer.Methods: 1236 patients (male 54.13% and female 45.87%) with psoriasis were seen in an Outpatient Clinic over a period of 8 years (2004&#1...

ea0035p263 | Clinical case reports Thyroid/Others | ECE2014

Coexisting hurthle cell neoplasm and thyroid hormone resistance

Yaylali Guzin Fidan , Erturk Mehmet Sercan , Akin Fulya , Yalcin Nagihan , Gurkan Hakan , Ozden Akin , Guldiken Sibel

Introduction: Resistance to thyroid hormone (RTH) is an inherited syndrome characterized by reduced responsiveness of target tissues to thyroid hormone (TH). It is characterized by high serum concentrations of free T4 (Ft4) and usually free T3 (Ft3) accompanied by normal or slightly high serum TSH concentrations. When RTH is suspected, the diagnosis should be confirmed by direct sequencing of the TR-β gene to identify mutations....

ea0035p264 | Clinical case reports Thyroid/Others | ECE2014

Primary hyperparathyroidism with severe hypercalcemia during pregnancy

Akin Fulya , Erturk Mehmet Sercan , Yaylali Guzin Fidan , Soysal Ergun

Introduction: Primary hyperparathyroidism (PHPT) commonly goes unrecognized due to the physiological changes of pregnancy.PHPT is associated with significant maternal and fetal morbidity and mortality. Current evidence supports parathyroidectomy is the main treatment, performed preferably during the second trimester, when the serum calcium is above 11–mg/dl. We report the clinical course of a woman with newly diagnosed gestational PHPT who refused minimally invasive parat...

ea0035p265 | Clinical case reports Thyroid/Others | ECE2014

Acute necrotizing pancreatitis as first manifestation of primary hyperparathyroidism

Tuzun Dilek , Kara Banu , Irkorucu Oktay

We present a case report of a young female patient with hypercalcemia-induced acute necrotizing pancreatitis as first manifestation of a benign parathyroid adenoma.Case: A 46-year-old female presented at the emergency room with a sudden attack of severe epigastric pain and vomiting. Clinical examination revealed a severely ill patient, a silent abdomen which was distended with painful percussion and palpation of the epigastrium. Blood analysis showed sig...

ea0035p266 | Clinical case reports Thyroid/Others | ECE2014

Is repeated fine needle aspiration expedient when the first one is nondiagnostic

Bubnov Alexander , Fedotov Yuriy , Chernikov Roman , Sleptsov Ilya , Timofeeva Natalya , Chinchuk Igor , Semenov Arseniy , Makarin Viktor , Uspenskaya Anna , Karelina Ulia , Novokshonov Konstantin , Fedorov Elisey , Rusakov Vladimir , Bichenkova Elisaveta , Isheiskaya Masha , Kulysh Aleksey , Vorobev Sergey

Background: It is disputable whether to repeat FNAB after the first one was nondiagnostic, or to submit the patient to operation.Methods: Indication for FNAB was a thyroid nodule of ≥1 cm or of a less size with clinical or ultrasound features of malignancy. In case of multinodular goiter each nodule was punctured and examined separately.3929 cases (8%) were noninformative out of 49 419 FNAB of thyroid nodules performed in Nor...

ea0035p267 | Clinical case reports Thyroid/Others | ECE2014

Analysis of 40 696 FNAB of thyroid nodules performed in one center

Bubnov Alexander , Fedotov Yuriy , Chernikov Roman , Sleptsov Ilya , Semenov Arseniy , Makarin Viktor , Chinchuk Igor , Timofeeva Nataly , Uspenskaya Anna , Novokshonov Konstantin , Karelina Ulia , Fedorov Elisey , Bichenkova Elisaveta , Isheiskaya Masha , Kulash Alex , Vorobev Sergey , Rusakov Vladimir

Background: Fine needle aspiration biopsy is generally acknowledged as a «gold standard» for diagnostics of thyroid malignancies. However, data on FNAB vary considerably in publications from different centers. In this study we have analyzed the results of more than 40 000 FNAB of thyroid nodules performed in North-West Regional Endocrine Center during 2010–2012 years.Subjects and methods: Indication for FNAB was a thyroid nodule of ≥...

ea0035p268 | Clinical case reports Thyroid/Others | ECE2014

Functional results of inadvertent parathyroid excision during thyroid surgery

Makarin Viktor , Bubnov Alexandr , Fedotov Yuriy , Chernikov Roman , Sleptsov Ilya , Rusakov Vladimir , Semenov Arseniy , Chinchuk Igor , Timofeeva Natalya , Novokshonov Konstantin , Karelina Ulia , Uspenskaya Anna , Fedorov Elisey , Kulash Alex , Vorobev Sergey , Ivanova Polina , Cheverda Olga , Bichenkova Elisaveta , Isheiskaya Masha

Background: Unintented parathyroidectomy during thyroid surgery – is one of typical complications, especially when an operation is augmented by lymphodissection. In this work, we present the results of calcium metabolism analysis in such patients.Subjects and methods: 3929 operations of patients with different thyroid diseases were performed during 2010–2012 years. 82 inadvertently excised parathyroid glands were revealed at histological examin...

ea0035p269 | Clinical case reports Thyroid/Others | ECE2014

Scleredema diabeticorum in a nonregulated type 2 diabetic patient

Ozsan Muge , Gulecol Seyma Celik , Ozbey Caner

Scleredema diabeticorum is an infrequently seen connective tissue disorder that effects upper part of the body. The affected skin is thick, hard and painless. A 51-year-old male Type 2 diabetic patient was referred to our department for infected foot ulcer. On physical examination erythematous, hard, painless, wide-reaching skin lesion on his upper back and shoulders except from draining diabetic foot ulcer on his right foot first and second fingers. Multipl subcutanously insu...

ea0035p270 | Clinical case reports Thyroid/Others | ECE2014

Rare coexistence of familial mediterranean fever and familial partial lipodystrophy: presented as acute pancreatitis due to severe hypertriglyceridemia

Gen Ramazan , Akbay Esen , Cinkir Umit , Sezer Kerem

A 21-year-old female (height: 148 cm, weight: 38 kg, and BMI: 17) was referred to our endocrinology outpatient polyclinic with the complaints of severe abdominal pain and severe hypertriglyceridemia. The patient’s medical history revealed diabetes and FMF. Physical examination revealed a marked loss of subcutaneous fat from the extremities leading to prominence of muscular contours and veins, with excess fat around the face, submental and dorsocervical region. Despite the...

ea0035p271 | Clinical case reports Thyroid/Others | ECE2014

Localized Aspergillus thyroiditis in patients with diabetic nephropathy

Horasan Elif Sahin , Gen Ramazan , Akbay Esen , Vayisoglu Yusuf , Kiyim Ahmet

Aspergillosis is a major problem in immunosupressed patients. We report a 65-year-old male patient with chronic renal failure (CRF) due to diabetic nephropathy who had arthralgy, malaise and high C-reactive protein level. Chest computed tomography revealed that thyroid nodule in the left thyroid lobe. Fine-needle aspiration biopsy of the thyroid revelead thyroidal invasion of Aspergillus. High-resolution computed tomograghy (HRCT) of the chest showed no evidence of intrapulmon...

ea0035p272 | Clinical case reports Thyroid/Others | ECE2014

Drug-induced syndrome of inappropriate antidiuretic hormone secretion

Majanovic Sanja Klobucar , Zoric Cedomir , Bicanic Nenad , Orlic Zeljka Crncevic

Introduction: Hyponatraemia is one of the most common electrolyte abnormalities that may be drug-induced either as a result of inappropriate antidiuretic hormone secretion (SIADH) or excessive sodium loss. SIADH is diagnosed on the basis of low plasma osmolarity associated with inappropriately concentrated urine.Case report: A 67-year-old woman was admitted to hospital because of progressive confusion and perseveration. Her medical history included bipol...

ea0035p273 | Clinical case reports Thyroid/Others | ECE2014

Heparin-induced hyperkalaemia in a patient with type 2 diabetes: a case report

Gandhi Nirav , Sharif Walid , Shakher Jayadave , Sharif Zuhair

Introduction: Heparin is extensively used amongst different medical and surgical specialities for prophylaxis and treatment of venous thromboembolism and suspected coronary syndromes. Hyperkalaemia is known to occur as an effect of heparin treatment through its action on the renin-angiotensin system, especially when used at treatment doses. Hyperkalaemia is a serious electrolyte disturbance, which may precipitate potentially fatal cardiac arrhythmias. We describe a case of a p...

ea0035p274 | Clinical case reports Thyroid/Others | ECE2014

A rare variant of papillary carcinoma of thyroid: Warthin-like variant

Bahadir Cigdem Tura , Kan Elif Kilic , Gokosmanoglu Feyzi , Atmaca Aysegul , Kefeli Mehmet

Introduction: Warthin-like papillary thyroid carcinoma (WLPTC) is a rare variant of thyroid papillary carsinoma (TPC). We present these cases to point out this rare variant.Case reports: Case 1: A 38-year-old woman admitted to outpatient clinic with a thyroid nodule. Ultrasonography of thyroid gland revealed bilateral multinodular goiter with microcalcifications. Thyroid autoantibodies were elevated. Thyroid function tests (TFT) were normal. Fine-needle ...

ea0035p275 | Clinical case reports Thyroid/Others | ECE2014

Mixed medullary and papillary carcinoma of thyroid

Bahadir Cigdem Tura , Gokosmanoglu Feyzi , Kan Elif Kilic , Atmaca Aysegul , Kefeli Mehmet , Akpinar Sinan

Introduction: Despite having different embriogenic origins, thyroid medullary carcinoma and follicular carcinoma may be seen together as mixed medullary-follicular thyroid carcinoma. We present a rare case of mixed medullary-follicular cell carcinoma of thyroid which has a progressive and aggressive nature.Case report: A 68-year-old female patient admitted with complaint of a lump in her neck. Ultrasonography of thyroid gland revealed a 37×35 mm sol...

ea0035p276 | Clinical case reports Thyroid/Others | ECE2014

Morphological and functional imaging allow better characterization of brown tumors in a patient with severe primary hyperparathyroidism

Vija Lavinia , Paun Diana , Grimon Gilles , Archambaud Frederique , Chaumet-Riffaud Philippe

Introduction: Brown tumors are rare, destructive, osteolytic bone lesions, occurring in advanced stages of hyperparathyroidism, due to increased osteoclastic activity.Case report: A 25-year-old woman presented with recent, intractable pain on the right shoulder and with hypercalcemia (Ca, 3.93 mmol/l) related to severe primary hyperparathyroidism (PTH, 494 pg/ml). Multiple osteolytic lesions, detected on the upper extremity of the right humerus, distal r...

ea0035p277 | Clinical case reports Thyroid/Others | ECE2014

When mother and daughter become father and son

Sajevets Tatjana , Verroken Charlotte , Heylens Gunter , Baere Elfride De , T'Sjoen Guy

Gender dysphoria (GD) leading to hormonal treatment and sex reassignment surgery that spans two generations has not been reported so far.The mother was diagnosed with GD at the age of 47. As an only child she suffered from emotional, physical, and sexual abuse by her parents. From the age of 3, she fantasized being a boy and started behaving like one. During later youth the genderdysphoric feelings were repressed. She married at the age of 18. One year l...

ea0035p278 | Clinical case reports Thyroid/Others | ECE2014

Giant mediastinal parathyroid cyst with hyperparathyroidism: a case report

Gabalec Filip , Svilias Ioannis , Hornychova Helena , Habal Petr , Cap Jan

Primary hyperparathyroidism (PHPT) is rarely caused by parathyroid adenoma with cystic degeneration, especially by the cyst localized in mediastinum. Both differential diagnosis of mediastinal cyst and management of the patient can be challenging.Case presentation: A 57 years old woman was transferred from district hospital where her urosepsis and nephrolithiasis had been treated successfully. A liquid collection in left hemithorax had also been found du...

ea0035p279 | Clinical case reports Thyroid/Others | ECE2014

Three endocrine neoplasms: an unusual combination of pituitary adenoma, papillary thyroid carcinoma, and follicular thyroid carcinoma

Kaya Mina Gulfem , Dellal Fatma Dilek , Kaya Cafer , Altunkaya Canan , Ersoy Reyhan , Cakir Bekir

Background: Differentiated thyroid cancer is the most frequent thyroid tumor. Combinations of follicular carcinoma and papillary carcinoma are seen. Functional pituitary adenoma coexisting with differentiated thyroid carcinoma was reported previously in literature. We report a 47-year-old women with three different synchronous endocrine tumors; papillary thyroid cancer, follicular thyroid cancer, and prolactinoma.Case: A 47-years-old female patient was a...

ea0035p280 | Clinical case reports Thyroid/Others | ECE2014

Not a make-up, but an alarm signal of a new onset of Addison's disease

Stanciu Roxana , Brzezinski Piotr , Foia Liliana , Chiriac Anca

Case report: A 52-year-old woman had an appointment at the dermatology department for a previous diagnosis of melasma. She was seen in October and her pigmentation had appeared somewhere during summer. She did not recall any drug intake, she denied sun exposure in the recent past, and she was a social employee working indoor.At the clinical examination intense hyperpigmentation around the eyes was noted. In contrast with the rest of the skin of normal as...

ea0035p281 | Clinical case reports Thyroid/Others | ECE2014

A carotid body tumor mimicking a thyroid nodule: a case report

Baser Husniye , Ayhan Baris , Karanis Meryem Ilkay Eren , Baser Salih , Karasoy Deniz , Kalkan Kemal , Ecirli Samil

Introduction: The cases of paragangliomas (PGLs) mimicking thyroid nodules were also reported in literature rarely. We will present a case of PGL (a carotid body tumor) that we initially evaluated as a thyroid nodule, and then diagnosed as a PGL.Case report: A 74-year-old woman was admitted due to a mass in the right side of neck growing rapidly within the last 1 month. Physical examination revealed a hard and painless mass with smooth surface, extending...

ea0035p282 | Clinical case reports Thyroid/Others | ECE2014

An uncommon infiltrative disease of thyroid: Riedel's thyroiditis

Gul Ozen Oz , Cander Soner , Ersoy Canan

Introduction: Riedel’s thyroiditis, also known as invasive fibrous thyroiditis, is a rare disorder of unknown etiology in which characterized by invasive fibrosis that partially destroys the thyroid gland and extends into adjacent neck structures. The diagnosis of Riedel’s thyroiditis is clinically difficult because this form of thyroiditis can mimic lymphoma or Hashimoto’s thyroiditis during preoperative radiologic, and pathologic examination. Sonographic featu...

ea0035p283 | Clinical case reports Thyroid/Others | ECE2014

Primary hyperparathyroidism due to parathyroid carcinoma: case report

Zwolak Agnieszka , Dabrowska Anna , Tarach Jerzy

Introduction: About 1% of primary hyperparathyroidism is due to parathyroid carcinoma. The affected gland is often indistinguishable from atypical adenoma. The proper diagnosis is usually made when the disease recurs or metastases are present and then is connected with poor prognosis.Case report: A 49-year-old man, after resection of parathyroid adenoma (postoperatively with normalization PTH concentrations and hungry bone syndrome), with limbs’ fra...

ea0035p284 | Clinical case reports Thyroid/Others | ECE2014

A rare cause of hypocalemia: familial hypoparathyroidism

Bahceci Mitat , Salgur Fusun , Tutuncuoglu Aliye Pelin , Yilmaz Husnu , Oruk Gonca

Background and aim: HDR syndrome, is a rare disease characterized with hypoparathyroidism, sensorineural deafness, and renal disease. Patients usually present with hypocalcaemia, tetany, or afebrile convulsions. Hearing loss is usually bilateral. Renal disease includes renal dysplasia, hypoplasia or aplasia. We report a Turkish family of HDR syndrome.Cases: A 56-year-old hypocalcemic deaf male patient and his daughter (25 years) and son (21 years) with h...

ea0035p285 | Clinical case reports Thyroid/Others | ECE2014

The coexistence of anaplastic thyroid carcinoma and papillary thyroid carcinoma: two case reports

Baser Husniye , Kaya Mina Gulfem , Polat Sefika Burcak , Dumlu Ersin Gurkan , Altunkaya Canan , Kilic Mehmet , Ersoy Reyhan , Cakir Bekir

Introduction: Anaplastic thyroid carcinomas (ATCs) are sometimes accompanied by well-differentiated carcinomas (WDCs), and ATCs have been speculated to be dedifferentiated from the preexisting or coexisting WDCs. We will present two cases determined with both ATC and papillary thyroid carcinoma (PTC.)Case 1: A 82-year-old woman was investigated due to a painful neck mass. Thyroid function tests were normal. Thyroid ultrasonography revealed isohypoechoic ...

ea0035p286 | Clinical case reports Thyroid/Others | ECE2014

One month-Tadalafil 5 mg once daily administration improves clinical and ultrasound parameters of chronic pelvic pain syndrome/lower urinary tract symptoms

Lotti Francesco , Corona Giovanni , Maggi Mario

Introduction: Tadalafil 5 mg once daily (T5od) has been recently approved by the Food and Drug Administration for the treatment of lower urinary tract symptoms (LUTS), along with erectile dysfunction (ED). Recent pooled data analyses demonstrated that T5od–International Prostate Symptom Score related improvements were significant regardless of confounders. In addition, PDE5 inhibitors exert a positive effect on ejaculatory latency. We assessed the clinical outcome of 30 d...

ea0035p287 | Clinical case reports Thyroid/Others | ECE2014

Recurrent episodes of hypoglycemia caused by insulinoma in a patient with type 2 diabetes mellitus

Blanco Manuel Cayon , Mateos Carolina Garcia-Figueras , Marin Patricia Rubio

Introduction: Hypoglycemia is the most frequent metabolic complication observed in patients with type 2 diabetes mellitus (T2DM). Moreover, rare insulinomas are the most common cause of endogenous hyperinsulinemic hypoglycemia in adults. The coincidence of insulinoma in a patient with pre-existing T2DM is an extremely rare condition and there are few case reports in the medical literature.Case report: A 76-year-old woman diagnosed with T2DM 6 years ago, ...

ea0035p288 | Clinical case reports Thyroid/Others | ECE2014

Primary hyperparathyroidism due to ectopic mediastinal parathyroid gland at the level of anterior wall of ascending aorta

Gogali Foteini , Tzatzadakis Nikolaos , Proikaki Stella , Samartzis Georgios , Prokovas Ioannis , Tsentidis Charalampos

Introduction: Parathyroid adenoma is the most common cause of primary hyperparathyroidism (PHPT) resulting in hypercalcemia and hypercalciuria due to autonomous secretion of PTH. Ectopic parathyroid adenoma, as a consequence of variability in the glandular tissue migration during the embryologic life or a supernumary fifth parathyroid gland, has an incidence of 25% among patients with PHPT. The incidence of deeply mediastinal ectopic parathyroid adenoma is 1–3%.<p cla...

ea0035p289 | Clinical case reports Thyroid/Others | ECE2014

Rhabdomyolysis precipitated acute renal injury during levothyroxine withdrawal for remnant ablation in a case with papillary thyroid cancer

Mousa Umut , Koseoglulari Osman , Sav Hasan

Ever since the approval of recombinant human TSH (rhTSH) prior to remnant ablation and whole body scans, usage of levothyroxine withdrawal for TSH elevation is decreasing. However the readily unavailability of rhTSH in some countries and the cost are its disadvantages. Withdrawal of levothyroxine, however, exposes the subjects to hypothyroidism.A 26-year-old male patient admitted to our hospital for a routine checkup with no symptoms. His TSH level was 7...

ea0035p290 | Clinical case reports Thyroid/Others | ECE2014

46,XX/47,XXY mosaic form of klinfelter syndrome with ambiguous genitalia: a case report

Chabour Fadila , Azzoug Said , Rabehi Leila , Chentli Farida

Klinefelter’s syndrome (KS) is the most frequent form of sex chromosome aneuploidy. The classic form of KS is associated with a 47,XXY karyotype. Mosaic forms of KS are thought to occur in approximately 10% mainly in the form of 46,XX/47,XXY. Other forms of mosaicism are rare among which the 46,XX/47,XXY form is very rare and can manifest as an ambiguous genitalia at birth as reported in our case.A full term child presented at birth an hypospadias w...

ea0035p291 | Clinical case reports Thyroid/Others | ECE2014

Primary hyperparathyroidism caused by mediastinum located ectopic parathyroid adenoma resected by video-assisted thoracic surgery

Imga Narin Nasiroglu , Karakurt Ozgur , Dogan Bercem Aycicek , Karabulut Zeynep , Tutuncu Yasemin , Berker Dilek , Kocer Bulent , Guler Serdar

Introduction: Ectopic parathyroid adenomas are detected 16% of patients operated for primary hyperparathyroidism and 22% of them may be located in the anterosuperior mediastinal region. Herein we present a rare case of primary hyperparathyroidism with severe long-term elevated parathormone (PTH) levels due to ectopic parathyroid adenoma in mediastinal region that was successfully treated by using video-assisted thoracic surgery (VATS).Case report: A 38-y...

ea0035p292 | Clinical case reports Thyroid/Others | ECE2014

Insulinoma and pregnancy: a case report

Saraoui Fatima , Azzoug Said , Rabehi Leila , Chentli Farida

Insulinoma is the most common cause of hypoglycemia related to endogenous hyperinsulinism in adults. It is very rare in pregnancy, fewer than 30 cases of insulinoma presenting in pregnancy have been reported so far and it’s managment is very challenging. We raported here the case of a pregnant women aged 35 years presenting an insulinoma.The diagnosis was made 1 year ago in the presence of hypoglycemia, high levels of inulin and C-peptide and a 10 m...

ea0035p293 | Clinical case reports Thyroid/Others | ECE2014

Excessive stimulation of TSH receptor during pregnancy

Lomna-Bogdanov Elzbieta

We are presenting a female, aged 34, who underwent two pregnancy miscarriages, in the 7th and 8th weeks. The first studies of thyroid hormones were made during the second pregnancy, and pointed to hyperthyroidism.After the loss of her second pregnancy, she was diagnosed for thyroid disease and miscarriages. TSH, FT3, FT4, antibodies TPO, TG, and TRAB were normal. Ultrasound examination showed symmetrical thyroid, not enlarged, with ...

ea0035p294 | Clinical case reports Thyroid/Others | ECE2014

Brown tumors: the first and the final manifestation of primary hyperparathyroidism.

Sztembis Joanna , Orlowska-Florek Renata , Dryja Agata , Swider Grzegorz

Introduction: Brown tumor–well circumscribed lytic lesion is one of the complication of advanced stage of primary and secondary hyperparathyroidism. It may be also a first clinical sign of primary hyperparathyroidism. Nowadays this is rare manifestation in developed countries due to increased use of routine screening laboratory examinations. Brown tumors may also mimic true neoplasm and lead to misdiagnosis if close attention is not paid. We present three case reports and...

ea0035p295 | Clinical case reports Thyroid/Others | ECE2014

Oncocytic carsinoma with sternum metastasis

Sahin Murat , Oguz Ayten , Tokur Mahmut , Yuzbasioglu Fatih , Sayar Hamide , Sahin Hatice , Gul Kamile

Introduction: Oncocytic (Hurthle cell) carcinoma is consisted of <5% of thyroid cancer but most metastasizing cancer type among differentiated thyroid cancer. We presented an oncocytic carcinoma with sternum metastasis.Case: A 68-year-old women admitted to endocrinology policlinic with complaint of a mass in her neck. She was diagnosed hyperthyroidism and she was using thionamid for 6 months. Her medical history revealed hypertension for 3 years and ...

ea0035p296 | Clinical case reports Thyroid/Others | ECE2014

Type 2 polyglandular autoimmune syndrome and Turner syndrome

Moreno Carolina , Rodrigues Dircea , Vieira Alexandra , Ruas Luisa , Saraiva Joana , Guelho Daniela , Cardoso Luis , Vicente Nuno , Carrilho Francisco

Introduction: Individuals with Turner syndrome (TS) are prone to develop autoimmune conditions. The most frequently found are Hashimoto’s thyroiditis, type 1 diabetes, coeliac disease, and inflammatory bowel disease. In patients with TS, Addison’s disease isolated or combined with other autoimmune disease as type 2 polyglandular autoimmune syndrome, is a rare finding.Case report: We report a case of a 41-year-old female patient, with severe ast...

ea0035p297 | Clinical case reports Thyroid/Others | ECE2014

Thyroid squamous cell carcinoma

Lichiardopol Corina , Surlin Valeriu , Ghilusi Mirela , Bondari Simona , Stancu Irina

Introduction: Squamous cell carcinoma (SCC) is a very rare thyroid carcinoma with aggressive behavior and poor prognosis. Diagnostic difficulties reside in differentiating SCC from other thyroid malignancies and also in establishing its primary or secondary nature, which are both important for treatment strategy.Case report: A 62-year-old woman, with unremarkable personal and family history, presented in October 2013 with progressive enlargement of a rig...

ea0035p298 | Clinical case reports Thyroid/Others | ECE2014

Patient with alopecia areata

Derkowska Ilona , Korzeniowska Katarzyna , Brandt Agnieszka , Buraczewska Marta , Mysliwiec Malgorzata

Introduction: Alopecia areata affects 0.1–0.2% of population. It’s pathogenesis has not yet been discovered, but genetic, autoimmune, vascular, psychogenic or neurological factors are being considered. It can occur in any age, but appears most commonly in late childhood, teenage or early adulthood. Alopecia areata commonly coexists with other diseases such as asthma, allergic rhinitis, atopic dermatitis, thyroid diseases and autoimmune diseases such as thyroiditis an...

ea0035p299 | Clinical case reports Thyroid/Others | ECE2014

Breast cancer in multiple endocrine neoplasia type 1

Elezovic Valentina , Petakov Milan , Macut Djuro , Ognjanovic Sanja , Isailovic Tatjana , Milicevic Ivana , Popovic Bojana , Antic Ivana Bozic , Bogavac Tamara , Ilic Dusan , Damjanovic Svetozar

Multiple endocrine neoplasia type 1 (MEN1) syndrome is an autosomal dominant familial tumor syndrome characterised by varying combinations of endocrine and non-endocrine tumors. Breast cancer is the most frequently diagnosed cancer in women, but presence of breast cancer in MEN1 is extremely rare.A 36-year-old patient has been diagnosed with primary hyperparathyroidism, breast cancer and hyperprolactinemia due to a pituitary macroprolactinoma. Treatment ...

ea0035p300 | Clinical case reports Thyroid/Others | ECE2014

Congenital TBG production disorder

Cepkova Jitka

Introduction: We describe the case of 35-year-old man in whom laboratory abnormalities in thyroid function were observed by chance.Case report: For the first time, the patient was examined in the local Department of Internal Medicine because of pre-arthroscopy examination in March 2002. Low level of total thyroid hormones (T3 0.76 nmol/l and T4 48.0 nmol/l) was observed by chance, while TSH value was normal (2.37 mIU/l). The patient...

ea0035p301 | Clinical case reports Thyroid/Others | ECE2014

Ectopic lingual thyroid gland: two case report

Gul Kamile , Sahin Murat , Oguz Ayten , Cangur Can , Ozkaya Mesut , Sagliker Hasan Sabit

Aim: Thyroid tissue originates from foramen cecum located in the base of the tongue and with embryonal development it descends through thyroglossal duct to its normal location. A total or partial failure in thyroid tissue descending causes ectopic thyroid tissue. One of this ectopic region is lingual region. We presented two case of ectopic thyroid tissue.Case 1: A 18-year-old female that uses levothyroxine 100 mcg/day for hypothyroidism admitted to endo...

ea0035p302 | Clinical case reports Thyroid/Others | ECE2014

An unusual case of diabetes mellitus as a result of heterozygous missense mutation R482W in LMNA gene (familial partial lipodystrophy type 2), described for the first time in Russian population

Sorkina Ekaterina , Tiulpakov Anatoly , Kalashnikova Marina , Melnichenko Galina

Background: Familial partial lipodystrophy type 2 (Dunnigan syndrome and FPLD2) is a rare genetic disorder, associated with different metabolic abnormalities, especially insulin resistant diabetes mellitus, dyslipidaemia, hepatic steatosis, and cirrhosis, cardiovascular disease, and cardiomyopathy, kidney disease.Clinical case: A 20-year-old patient first presented with changed appearance due to abnormal subcutaneous fat tissue redistribution (lipodystro...

ea0035p303 | Clinical case reports Thyroid/Others | ECE2014

A patient with lung ectopic parathyroid coexistent with primary hyperparathyroidism and end-stage renal diseases

Kowalska Beata , Lomna-Bogdanov Elzbieta , Pukajlo Katarzyna , Kaluzny Marcin , Jedrzejuk Diana , Doskocz Krzysztof

We report the case of 57-year-old man with end-stage renal disease, primary hyperparathyroidism and after an surgery of upper parathyroid glands with ectopic parathyroid localized in lung. Patient was directed to our hospital to perform diagnostics on hyperparathyroidism. Two years earlier (2011) patient was hospitalized because of weakness and weight loss, and was diagnosed with primary hyperparathyroidism. In 2012 he underwent the bilateral parathyroidectomy of upper glands ...

ea0035p304 | Clinical case reports Thyroid/Others | ECE2014

Graves–Basedow disease in adolescent patients with type 1 diabetes mellitus

Korzeniowska Katarzyna , Derkowska Ilona , Sztangierska Beata , Mysliwiec Malgorzata

The prevalence of GD (Graves–Basedow disease) in adolescents with T1DM (type 1 diabetes mellitus) is around 0.5%. Most often the diagnosis of GD in T1DM patients is made many years after the onset of T1DM. The present clinical case describes an adolescent with GD and T1DM and highlights how difficult the management of this disease can be. 17-year-old male was referred to our Department for reevaluation of Graves–Basedow disease. Patient suffered from T1DM for 14 year...

ea0035p305 | Clinical case reports Thyroid/Others | ECE2014

Follicular thyroid carcinoma presenting with occipital bone and lung metastasis

Sacikara Muhammed , Aydin Cevdet , Saglam Fatma , Poyraz Nilufer Yildirim , Kandemir Zuhal , Yazgan Aylin Kilic , Ersoy Reyhan , Cakir Bekir

When follicular thyroid carcinoma (FTC) is diagnosed, 25% of the patients extrathyroidal invasion, 5–10% lymphatic metastasis and 10–20% distant metastasis are determined. The most common site of distant metastases of FTC is the lung, followed by the bone. The incidence of skull metastasis of FTC is about 2.5–5.8%. Skull metastasis of FTC was located in the skull base and occipital area.Case: A 60-year-old man admitted at 2006. He was oper...

ea0035p306 | Clinical case reports Thyroid/Others | ECE2014

Long-term use of tolvaptan in hyponatraemia due to SIADH in elderly

Pothina Narayana Prasad , Sathyapalan Thozhukat

Background: Hyponatraemia is the most common electrolyte disorder seen in clinical practice. Even mild hyponatraemia can lead to gait disturbances and cognitive dysfunction in the elderly.Case history: A 83-year-old lady presented to acute admission unit with worsening of confusion. Her background medical history includes chronic obstructive pulmonary disease for which she is on inhalers. She was also having hyponatraemia for the last 3 years manifesting...

ea0035p307 | Clinical case reports Thyroid/Others | ECE2014

Challenges in exophthalmia management: Frontal mucocele

Toma Nicoleta , Mocanu Bogdan , Daniela Alexandrescu , Badiu Corin

Frequently seen in connection with thyroid disease, exophtalmic syndrome has a much large spectrum of differential diagnosis including numerous local and general aetiologies. Conditions such as mucoceles of paranasal sinuses don’t have always nasal or sinus symptoms but may present with ophthalmological manifestations.A 50-year-old woman presented for a 2-months history of right eye proptosis with upper eyelid swelling, periorbital pain, occasionall...

ea0035p308 | Clinical case reports Thyroid/Others | ECE2014

Testicular histological and immunohistochemical particularities in a post-pubertal patient with 5α-reductase type 2 deficiency

Vija Lavinia , Ferlicot Sophie , Paun Diana , Bry-Gauillard Helene , Lombes Marc , Young Jacques

Introduction: Testicular morphology and immunohistochemistry have never been reported in genetically documented adult patients with 5α-reductase type 2 deficiency (5α-R2 deficiency).Case report: We describe the testicular histopathology of a 17-year-old XY female with primary amenorrhea, failure of pubertal breast development, virilization, clitoromegaly, and bilateral cryptorchidism (testes located in the inguinal canals). The diagnosis of 5&#...

ea0035p309 | Clinical case reports Thyroid/Others | ECE2014

Treatment of hyponatraemia with vasopressin receptor 2 antagonists (V2RA): case series

Rys Andrzej , Lissett Catherine

Vasopressin receptor 2 antagonist (V2RA) provide treatment option for patients with hyponatraeamia in the context of syndrome of inappropriate antidiuretic hormone secretion (SIADH).We report the results of seven patients (six males, one female, average age 65.7) with hyponatraemia secondary to SIADH treated with V2RA (Tolvaptan) in years 2011–2013. Six patients had underlying diagnosis of lung cancer, one patient was diagnosed with sarcoidosis. Fou...

ea0035p310 | Clinical case reports Thyroid/Others | ECE2014

Do clinical events always suggest familial form of medullary thyroid carcinoma (MTC)? – two case reports

Bajkin Ivana , Novakovic-Paro Jovanka , Icin Tijana , Mitrovic Milena , Vukovic Bojan , Popovic Djordje , Milankov Andrijana , Kovacev-Zavisic Branka , Medic-Stojanoska Milica

Introduction: MTC originates from the parafollicular calcitonin secreting cells. One quarter of MTC patients have familial form of the disease with RET mutation.Case reports: First female patient underwent total thyroidectomy for MTC at the age 40. Further investigation showed elevated urinary catecholamine levels and MIBG scintiscan verified bilateral pheochromocytoma. Bilateral adrenalectomy was performed. On follow-up basal and stimulated calcitonin l...

ea0035p311 | Clinical case reports Thyroid/Others | ECE2014

A rare case of cutaneous metastization of a differentiated thyroid carcinoma initially diagnosed as Hurthle cell adenoma

Castedo Jose-Luis , Costa Maria Manuel , Pimenta Tiago , Pestana-Silva Roberto , Carvalho Davide

Introduction: Cutaneous metastization of differentiated thyroid carcinomas is a rare event.Clinical case: MMS, a 69-year-old male was submitted to left hemithyroidectomy+isthmectomy on May 2006 after FNA of a left node revealed follicular tumor. Histology showed Hurthle cell adenoma. The patient maintained irregular follow-up by endocrinologist. In October 2011 he referred the appearance of small bilateral cervical skin nodules. Physical exam showed thre...

ea0035p312 | Clinical case reports Thyroid/Others | ECE2014

Diagnosis of neonatal diabetes mellitus in the mother through the detection of hyperglycemia in her child

Torres Isabel , Santos M Angeles , Castano Luis

Introduction: Neonatal diabetes mellitus (NDM) is a rare disease diagnosed within the first months of life that is usually permanent in 50% of cases. Heterozygous mutations of KCNJ11 and ABCC8 genes encoding the two Kir6.2 and SUR1 subunits of the b-cell ATP-dependent potassium channel have been associated with NDM, which is characterized by a successful response to sulfonylureas.Case report: We present a 32-year-old woman diagnosed wit...

ea0035p313 | Clinical case reports Thyroid/Others | ECE2014

Ectopic co-secretion of growth hormone and growth hormone-releasing hormone from a neuroendocrine lung tumor in a patient with MEN1 syndrome

Isailovic Tatjana , Todorovic Vera , Milicevic Ivana , Petakov Milan , Macut Djuro , Ognjanovic Sanja , Elezovic Valentina , Skender-Gazibara Milica , Popovic Bojana , Antic Ivana Bozic , Bogavac Tamara , Ilic Dusan , Damjanovic Svetozar

The co-secretion of GHRH and GH has been described previously in a patient with GHRH producing pituitary somatotroph adenoma. Here we present a patient with MEN1 and ectopic secretion of both GHRH and GH from a neuroendocrine lung tumor.A 52-year-old woman was diagnosed in 2009 with two lung tumors, 4 cm right upper lobe tumor, and 2 cm left lower lobe tumor. Owing to a mild coarsening of facial features, acromegaly was suspected. Endocrine studies showe...

ea0035p314 | Clinical case reports Thyroid/Others | ECE2014

Refractory Graves' ophthalmopathy treated with rituximab

Adamidou Fotini , Poulasouhidou Maria , Boboridis Kostas , Hambidis Vassilis , Anagnostis Panagiotis , Kita Marina

Introduction: Graves’ ophthalmopathy (GO) is common in the course of Graves’ disease, but optic neuropathy is present in only ~5% of patients with GO. We present a case of recalcitrant Graves’ orbitopathy with late development of neuropathy, satisfactorily treated with rituximab.Case report: A 50-year-old female smoker was referred to our department for further management of Graves’ disease with associated GO. She complained of worsen...

ea0035p315 | Clinical case reports Thyroid/Others | ECE2014

Drug induced skin eruption in type 2 diabetes mellitus patients who treating with a dipeptidyl peptidase-4 inhibitor plus metformin

Gul Ozen Oz , Cander Soner , Gul Bulent , Tuncel Ercan , Ersoy Canan

Background: Incretin-based therapy is increasingly used in the management of type 2 diabetes mellitus. Although dipeptidyl peptidase-4 inhibitors (gliptins) are well tolerated, side effects can be observed in various body systems. Here we report three cases of drug-induced skin eruption with strong itching of the gliptins plus metformin combination therapy.Case reports: A 59-year-old woman and a 57-year-old man, who had been using vildagliptin plus metfo...

ea0035p316 | Clinical case reports Thyroid/Others | ECE2014

Severe postmenopausal virilization of unknown origin

Matyjaszek-Matuszek Beata , Lenart-Lipinska Monika , Tarach Jerzy

Introduction: The severe course of hyperandrogenism during the menopausal transition requires the exclusion of androgen-secreting tumors.Case report: A 60-year-old postmenopausal woman was referred to the Department of Endocrinology with a 3-year history of progressive development of hyperandrogenism with virilization (severe hirsutism, frontal balding, deepening of voice, increased muscle mass, and secondary polycythemia).Hormonal...

ea0035p317 | Clinical case reports Thyroid/Others | ECE2014

Propylthiouracil induced lupus erythematosus in a patient with Grave's disease: a case report

Keri Denisa , Hoxha Violeta , Kermaj Marjeta , Zeqja Anisa , Husi Gerond , Ylli Agron

Introduction: Drug-induced lupus erythematosus (DILE) is a variant of systemic lupus erythematosus that resolves within days to months after withdrawal of the drug, in a patient with no previous history of SLE.Case report: A 60-year-old female presented at Mother Teresa Hospital with toxic multinodular goiter. She received treatment with propylthiouracil and atenolol for a month, and she developed symptoms like malaise, muscle pain, shortness of breath, ...

ea0035p318 | Clinical case reports Thyroid/Others | ECE2014

Monomorphic ventricular tachycardia due to primary hyperparathyroidism: a case report

Gomes Ana Coelho , Vale Sonia do , Cruz Diogo , Martins Joao Martin , Martins Ana Filipa , Tavares Filipa , Santos Vera Costa , Colaco Ines , Pereira Guilherme , Guimaraes Tatiana , Oliveira Anabela

Introduction: Cardiovascular changes are rare but life-threatening consequences of primary hyperparathyroidism.Case report: A 53-year-old man, with past and family history of peptic ulcer, presenting with coronary heart disease and ischemic and dilated cardiomyopathy, treated with cardiac resynchronization. He was admitted to the emergency room due to sustained monomorphic ventricular tachycardia (MVT). Laboratory tests revealed primary hyperparathyroidi...

ea0035p319 | Clinical case reports Thyroid/Others | ECE2014

The unusual case of the appearance of radioiodine (I-131) uptake in lung metastases in a patient with papillary thyroid cancer (PTC)

Palyga Iwona , Kowalska Aldona , Walczyk Agnieszka , Holody Lukasz

A 67-year-old male with PTC (pT3N0) underwent a total thyroidectomy in February 2004. Subsequently he was treated with I-131 and radiotherapy (RT). Combined therapy did not normalize the serum thyroglobulin (TG). Because of elevated TG and persistent I-131 uptake in thyroid bed the patient received a total activity of 21275 MBq of I-131 in 4 years. The treatment was stopped in March 2007 due to a lack of I-131 uptake in the last post-therapeutic whole body scan (WBS) with stil...

ea0035p320 | Clinical case reports Thyroid/Others | ECE2014

Recurrent debilitating thyroiditis

Abdin Ayman , Hussain Shazia , Hawkins Anna , Casey Edel , Nikookam Khash

Case: A 46-years-old anaesthetist presented with 2 weeks history of general malaise, sore throat, and fever. Symptoms started while on holiday. A diagnosis of subacute thyroiditis was made overseas based on presentation and suppressed TSH level. He was started on betamethasone 4mg and ibuprofen for 2 weeks with rapid symptomatic improvement. He felt well enough to travel back to UK. He then presented to our hospital with recurrent symptoms as above.Inves...

ea0035p321 | Clinical case reports Thyroid/Others | ECE2014

Hashimoto thyroiditis followed by Grave's disease

Ouldkablia Samia , Cheikh Assya , Bensalah Meriem , Aribi Yamina , Kemali Zahra

Introduction: Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are two auto-immune diseases. They have different phenotypes and are generally believed to share a number of common etiological factors but the mechanisms leading to their dichotomy are unknown. An unusual outcome of HT is the conversion to GD.A mechanism that might be hypothesized to account for the change from HT to GD is the alteration in the biological activity of TSH recep...

ea0035p322 | Clinical case reports Thyroid/Others | ECE2014

Why obesity is multifactorial? Mixture of genetic predisposition, endocrine dysfunction and environmental factors: a case report

Tejera Cristina , Beato Pilar Isabel , Rodriguez Raquel

Introduction: Obesity prevalence is growing every year. In most cases, origin is exogenous, a mixture of sedentary and overeating. However, some patients are trend to develop obesity caused by their genetics and other illness.Case report: A 62-year-old women with diabetes type 2, anxiety and osteoporosis was remitted to our center for obesity. She had been obese since childhood, with very low level of activity and snacking trend. On physical examination ...

ea0035p323 | Clinical case reports Thyroid/Others | ECE2014

Case study in PTU-induced hepatotoxicity: a retrospective analysis of the key aspects of survivability in PTU-induced hepatotoxicity in adults

Sardar Noel , Lulsegged Abbi , Asante Maxwell

A 20-year-old female patient with Graves’ disease was commenced on PTU 50 mg OD in June 2009 because of intolerance to carbimazole. She presented with jaundice within 5 months and was subsequently admitted when she started vomiting 2 months later.She had tenderness in the right upper quadrant. LFT on admission are alkaline phosphatase 268 μ/l (35–104), gamma glutamyl transferase 148 μ/l (5–36), aspartame transferase 194 μ/l ...

ea0035p324 | Clinical case reports Thyroid/Others | ECE2014

Meningioma in a patient with tall cell papillary thyroid carcinoma

Spyropoulos Panagiotis , Kostoglou-Athanassiou Ifigenia

Tall cell papillary thyroid carcinoma is known to be associated with an adverse outcome, namely with the early development of locally recurrent or metastatic disease. Therefore the administration of therapeutic radioactive iodine is considered absolutely necessary in the management of such patients. A meningioma may occur in a patient with another neoplastic disease, having also been described in patients with thyroid carcinoma.The aim was to describe th...

ea0035p325 | Clinical case reports Thyroid/Others | ECE2014

Hypoglycemia in type 1 diabetes mellitus patient – factual ou factitious?

Guelho Daniela , Paiva Isabel , Rodrigues Dircea , Baptista Carla , Saraiva Joana , Moreno Carolina , Dantas Rosa , Vicente Nuno , Cardoso Luis , Carrilho Francisco

Introduction: Factitious hypoglycemia results from surreptitious administration of insulin or insulin secretagogues. It can involve non-diabetic individuals with knowledge of hypoglycemiant drugs, or diabetics manipulating the doses.Clinical case: A 42-year-old women, type 1 diabetic since the age of 14, on intensive insulin therapy (A1C: 8.5%), was hospitalized for study of recurrent severe hypoglycemia in the last 2 months, despite successive insulin d...

ea0035p326 | Clinical case reports Thyroid/Others | ECE2014

From hemoptysis to diagnosis of congenital hypothyroidism: a diagnostic pitfall

Szkudlarek Malgorzata , Szczepanek-Parulska Ewelina , Ziemnicka Katarzyna , Piatek Katarzyna , Golab Monika , Kaluzny Jaroslaw , Czepczynski Rafal , Ruchala Marek

Introduction: Congenital hypothyroidism (CH) is the most common congenital endocrine disorder. It occurs in Europe with an incidence of 1:3000–1:4000.Thyroid dysgenesis – agenesis, hypoplasia or ectopy – is responsible for 80–90% of CH cases. An ectopic thyroid gland is an uncommon inborn anomaly and is typically located along the thyroglossal duct. To date only few cases of CH due to lingual thyroid diagnosed in adulthood were reported in the literature.</...

ea0035p327 | Clinical case reports Thyroid/Others | ECE2014

Hirata disease: a rare form of hyperinsulinemic hypoglycemia

Cardoso Luis , Church David , Rodrigues Dircea , Alves Marcia , Guelho Daniela , Saraiva Joana , Moreno Carolina , Dantas Rosa , Vicente Nuno , Semple Robert K. , Carrilho Francisco

Introduction: Insulin autoimmune syndrome or Hirata disease is a rare cause of hypoglycemia without prior insulin exposure. Approximately 400 cases were reported, mostly in Japan. It’s associated with other autoimmune diseases or exposure to sulfhydryl-containing drugs.Case report: A 56-year-old Caucasian woman presented with a 20-month history of hypoglycemia ameliorated by sugar intake. She had a past history of autoimmune thyroiditis, asthma and ...

ea0035p328 | Clinical case reports Thyroid/Others | ECE2014

Gynecomastia: a rare etiology

Vicente Nuno , Barros Luisa , Saraiva Joana , Moreno Carolina , Guelho Daniela , Cardoso Luis , Carrilho Francisco

Introduction: Gynecomastia is a frequent reason for endocrinology consultation and its correct investigation is pivotal towards a precise diagnosis. We present a clinical case of a rare cause of gynecomastia.Case report: A 56-year-old male was referred to the hospital setting for an endocrinology consultation. He noticed increased breast size for a year, initially tender to palpation, and unquantified weight loss. Neither galactorrhea, nor any nipple dis...

ea0035p329 | Clinical case reports Thyroid/Others | ECE2014

Two serious complications of propylthiouracil treatment in the same patient: case report

Garrido Susana , Pereira Teresa , Marinho Antonio , Freitas Claudia , Vilaverde Joana , Amaral Claudia , Carvalho Andre , Borges Fatima

Introduction: Thionamides are important drugs in the treatment of hyperthyroidism. Despite that, they can be associated with rare but serious complications, which require drug discontinuation.Case report: Sixty-five-year-old woman with Graves’ disease, treated in 2002 with methimazole and in remission until 2012. Recurrence of Graves’ disease was diagnosed in March 2012 and she was started on propylthiouracil (PTU) 150 mg per day. She presented...

ea0035p330 | Clinical case reports Thyroid/Others | ECE2014

Brain metastatic disease in a patient with tall cell thyroid carcinoma

Georgiadis Ioannis , Kostoglou-Athanassiou Ifigenia

Papillary thyroid carcinoma is a disease associated with a very good prognosis. However, there are some subtypes of papillary thyroid cancer which are associated with aggressive biological behavior and worse outcome. The appearance of brain metastatic disease in the course of papillary thyroid carcinoma is rare and carries an unfavorable prognosis.The aim was to describe the case of a patient with tall cell papillary thyroid carcinoma who presented with ...

ea0035p331 | Clinical case reports Thyroid/Others | ECE2014

Thyroid papillary microcarcinoma presenting as parotid metastasis: a case report

Garcia-Arnes Juan Antonio , Maldonado Cristina , Fernandez Rosario , Gonzalo Montserrat

Differentiated thyroid carcinoma is the most common endocrine malignant tumor. Papillary carcinoma frequency in our country is 80% of thyroid neoplasia. Papillary thyroid carcinoma usually metastasizes to cervical lymph. Metastases to distant organs are rare and most often affect the lungs, liver and bones. Despite of its anatomical proximity, metastasis parotid have not been described in the existing papillary carcinomas literature. We report a case of parotid gland metastasi...

ea0035p332 | Clinical case reports Thyroid/Others | ECE2014

Medullary and papillary thyroid cancer metastasis in the same lymph node: case report

Yilmaz Merve , Gedik Arzu , Ikiz Ahmet Omer , Gumus Tugba , Calan Mehmet , Tunc Ulku Aybuke , Canda Serafettin , Alacacioglu Ahmet , Comlekci Abdurrahman , Demir Tevfik

Introduction: Two tumors originating from different cells in the thyroid to metastasis same lymph nodes is very rare. We aimed to present that the same lymph node metastasis of medullary and papillary thyroid in a case.Case: A 4-year-old male presented with backache without a formerly known disease, has no other property in the patient’s history. Vertebra BT was taken and T2, T4, T6 vertebral metastasis have been det...