Searchable abstracts of presentations at key conferences in endocrinology
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16th European Congress of Endocrinology

Plenary Lectures

Advances in molecular pathogenesis of thyroid cancer therapeutic implications

ea0035pl2 | Advances in molecular pathogenesis of thyroid cancer therapeutic implications | ECE2014

Advances in molecular pathogenesis thyroid cancer: therapeutic implications

Santisteban Pilar , Sastre-Perona Ana , Wert-Lamas Leon , Riesco-Eizaguirre Garcilaso

Thyroid cancer is one of the endocrine pathologies whose incidence is increasing, although in general terms it has a good outcome. However, some patients develop aggressive forms that are untreatable and the molecular basis is poorly understood. These aggressive forms are basically well-differentiated thyroid carcinomas that undergo dedifferentiation and poorly differentiated and anaplastic carcinomas. All of them have lost Na/I Symporter (NIS) function leading to radioiodine-...