Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 35 | ECE2014 | Next issue

16th European Congress of Endocrinology

Oral Communications

Thyroid clinical

ea0035oc1.1 | Thyroid clinical | ECE2014

Esophagus motility in overt hypothyroidism

Ilhan Mahmut Muzaffer , Arabaci Elif , Turgut Seda , Karaman Ozcan , Danalioglu Ahmet , Tasan Ertugrul

Introduction: Gastrointestinal tract is one of the most affected systems in hypothyroidism. The most plausible mechanism in the pathogenesis is the development of interstitial edema subsequent to accumulation of glycosaminoglycans. Despite decreased esophageal emptying, prolonged esophageal and gastric transit time has been indicated in previous reports, the mechanism of thyroid hormones activity on the gastrointestinal system is not yet fully understood. To our knowledge, thi...

ea0035oc1.2 | Thyroid clinical | ECE2014

Levothyroxine substitution in subclinical hypothyroidism: Does it have a beneficial effect on all-cause mortality?

Andersen Mette Nygaard , Olsen Anne-Marie Schjerning , Madsen Jesper Clausager , Faber Jens , Torp-Pedersen Christian , H. Gislason Gunnar , Selmer Christian

Background: Subclinical hypothyroidism is associated with a number of cardiovascular risk factors such as hypertension, hypercholesterolemia, and diastolic dysfunction, but only limited data exist on long-term outcome of levothyroxine substitution therapy.Objectives: To examine effects of levothyroxine substitution treatment on mortality in patients with subclinical hypothyroidism.Study design: Historical cohort study.<p class=...

ea0035oc1.3 | Thyroid clinical | ECE2014

Chronic liothyronine (T3) treatment in stable heart failure patients with low T3 syndrome: A randomised, double-blind, cross-over, placebo-controlled intervention study (The LIHFA study)

Holmager Pernille , Schmidt Ulla , Dall Mark Peter , Dominguez Helena , Zerahn Bo , Raymond Ilan , Kistorp Caroline , Nygaard Birte , Faber Jens

Background and aim: Low T3 syndrome is associated with a poor prognosis in patients with chronic heart failure (CHF). It is controversial whether T3 treatment is indicated in CHF. A previous study using intravenous infusion of T3 for 72 h suggested a beneficial effect on cardiac performance.We aimed to evaluate the effect of 13 weeks of T3 treatment in patients with stable CHF on left ventricular ejection fraction (LVEF) compared to placebo.<p class=...

ea0035oc1.4 | Thyroid clinical | ECE2014

Consequences of experimental hyperthyroidism on brain structure and function in humans

Dirk Anna-Luise , Goebel Anna , Heldmann Marcus , Iwen Alexander , Brabant Georg , Munte Thomas

Objective: Disturbed levels of thyroid hormones are associated with neuropsychiatric disorders, including memory impairments. Even short-term hyperthyroidism may affect properties of the human brain. To investigate the influence of thyroid hormones, we conducted functional neuroimaging. The aim of this study was to evaluate functional changes in working memory performance.Materials and Methods: Twenty healthy, male, right-handed subjects (age range 21&#1...

ea0035oc1.5 | Thyroid clinical | ECE2014

rh-TSH (Thyrogen) aided radioiodine therapy in children and adolescents with DTC

Handkiewicz-Junak Daria , Roskosz Jozef , Gawlik Tomasz , Olczyk Tomasz , Gubala Elzbieta , Kropinska Aleksandra , Hasse-Lazar Kornelia , Jarzab Barbara

Background: Although recombinant human TSH (rhTSH) is widely used to aid radioiodine treatment of differentiated thyroid cancer (DTC), however, there are data on its effectivness in children and adolescents with DTC.The aim of our retrospective study was to evaluate effectiveness and safety of rhTSH aided radioiodine treatment in DTC patients 18 years of age or younger.Material and Methods: Fifty five children/adolescents (median a...