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Endocrine Abstracts (2014) 35 P72 | DOI: 10.1530/endoabs.35.P72

Service of Endocrinology Diabetes and Metabolic Diseases, Laboratory PCIM, FMPM, University Cadi Ayad, University Hospital Mohamed V, Marrakech, Morocco.


Introduction: Musculoskeletal manifestations of endocrine disorders are a heterogeneous group of disease, often giving rise to various clinical or radiological individuals. Osteoporosis is a not uncommon complication of endocrine disease. It may even be accompanied by endocrinopathy.

Aim of study: Determine mineral bone density profile of patients with endocrinopathy and define the characteristics of osteoporosis and osteopenia in these patients.

Patients and methods: Descriptive study concerning patients followed for endocrinopathy in the Service of Endocrinology and Diabetology of the University Hospital Mohamed V of Marrakech from January 2012 to January 2014.

Preliminary results: The sex ratio of patients is 0.26, with an average age of 37 and extreme ages of 16 and 73 years. 88% of patients had osteoporosis or osteopenia. 36% of them showed osteoporosis in femoral and vertebral site, and 20% at the spine. Osteopenia was found in 24% at the spine, 4% at the femoral site and 4% at the two sites. These abnormalities in bone density were revealed by the endocrine pathology in 76% of patients. The percentage of endocrinopathies responsible for its defects is as follows: 28% of hyperadrenocorticism, 28% of hypogonadotropic hypogonadism, 8% of hyperparathyroidism, 8% of hyperthyroidism.

Discussion: This work shows a high incidence of osteoporosis and osteopenia in patients treated for endocrine diseases and drove us to place the interests of systematically seek an abnormal bone density before any endocrine disorder which can cause rheumatic disorder.

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