Searchable abstracts of presentations at key conferences in endocrinology
Symposia
Androgens and disease progression in prostate cancer
ea0037s24.1 | Androgens and disease progression in prostate cancer | ECE2015
Leveraging circulating DNA studies to identify mechanisms of resistance to CYP17A1 inhibition
CYP17A1 inhibition with abiraterone is an effective treatment for castration-resistance prostate cancer (CRPC), with significant improvements in survival, radiological progression free survival, pain, skeletal related events and other secondary end-points. However, resistance invariably develops. Due to mineralocorticoid excess, abiraterone is administered with glucocorticoids. Next-generation sequencing of circulating plasma DNA from CRPC offers an opportunity to monitor tumo...
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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