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Endocrine Abstracts

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17th European Congress of Endocrinology

Plenary Lectures

Insulin signalling and action

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Congenital Adrenal Hyperplasia (CAH): Mechanisms and management across the life span
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ea0037pl5 | Insulin signalling and action | ECE2015

Interplay between genes and environment in insulin resistance and metabolic syndrome: the unique role of the gut microbiome

Kahn C Ronald , Ussar Siegfried , Fujisaka Shiho

Both type 2 diabetes (T2D) and obesity are the result of a complex interaction between genes and environment, as well as complex interactions between the tissues of the body. The latter include effects of new adipokines released by fat that influence insulin action in other tissues of the body, as well as increasingly complex effects of the brain and adipose tissue on control of metabolism. Mouse models provide a powerful tool to investigate these interactions in disease patho...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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