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Endocrine Abstracts (2015) 37 EP895 | DOI: 10.1530/endoabs.37.EP895

1Virgen del Rocio University Hospital, Seville, Spain; 2Thyroid Cancer working group, Andalusia, Spain; 3Institute of Statistics and Cartography, Andalusia, Spain.


Introduction: The incidence of thyroid cancer (TC) is low, but rising over time. Some studies point to a possible increase in mortality rate (MR) from this cancer in certain areas of Spain and Andalusia. Our purpose was to analyse the TC mortality in Andalusia and study how it has changed in the last years. We also analysed differences by age, sex, and geographic area.

Methods: All deaths from TC were collected between January 1, 1975 and December 1, 2011. These deaths were classified by age, sex, and province. Data were obtained from the mortality register of the Andalusian Statistics and Cartography Institute and from the Regional Ministry of Health. We calculated specific MR standardized by the direct and indirect method (standardized mortality ratio-SMR-) for all Andalusia and for each province.

Results: Between 1975 and 2011, 1199 TC deaths were registered in Andalusia (62.1% women). In these 37 years the MR has not changed significantly. The MR is higher in women (0.5–1 deaths/100 000 population-year) than in men (0.4–0.7 deaths/100 000 population-year); however, it has remained stable in both genders over time. Mortality increases exponentially with age, ranging MR from 0.02–0.1 deaths/100 000 population-year at 1930s up to 2–5 deaths/100 000 population per year at 1980s. Mortality is higher in men than in women up to 1940s, remains equal in both sexes between 1940s and 1970s and is higher in women over 1970s. There are small differences when comparing mortality in the Andalusian provinces. The SMR for whole Andalusia is 1. A SMR >1 indicates that there are more deaths observed than expected, as occurs in Seville, Granada, Cádiz and Huelva. Córdoba, Jaén, Almería and Málaga have a SMR <1.

Conclusions: Mortality from TC in Andalusia has remained stable over the last 37 years. There are differences in mortality in the Andalusian provinces. It is necessary to analyse the factors involved.

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