Endocrine Abstracts

Neuroendocrine tumors do not share many classical pathways of tumorigenesis with their non-endocrine counterparts. In recent years, the molecular understanding of of pancreatic neuroendocrine tumors (PanNET) tumorigenesis has made major advances. A whole exome NGS analysis described frequent mutations of two new genes DAXX and ATRX. 40% of unselected panNET show mutations in one of these genes. Mutations in these genes are associated with loss of the respecti...

Professor Aurel Perren is Director of the Institute of Pathology at the University Bern since 2009. He did his pathology training in Zürich with a special focus on endocrine tumors. 2007 he was appointed Professor of Pathology in the Technische Universität München. His research focus lies on the histopathological, molecular and genetic analysis of familial and sporadic NEN with a special interest in pancreatic NEN. He was involved in the WHO classification of en...