Endocrine Abstracts (2016) 40 P23 | DOI: 10.1530/endoabs.40.P23

A rare synchronous presentation of aldosterone producing adenoma and multifocal papillary thyroid microcarcinoma

M Davitadze1, D Metreveli1,2, I Gudushauri1 & K Mikadze1

1V. Iverieli Endocrinology, Metabology, Dietology Center “ENMEDIC”, Tbilisi, Georgia; 2Tbilisi State Medical University, Tbilisi, Georgia.

Introduction: In this report, we describe a rare coexistence of a multifocal papillary thyroid (micro)carcinoma and aldosterone-producing adenoma.

Case presentation: A 60-year-old man attended our clinic with a mass in the right adrenal gland was identified during the work-up in 2007. The patient presented complaints on anxiety, tachycardia, and arterial hypertension. He had several episodes of severe hypertension (220/120 mmHg) while sleeping. In 2014, an ultrasound guided fine needle aspiration of the thyroid nodule was performed; cytology showed Hurthle cell neoplasm suspicious for malignancy. The diagnosis was confirmed by laboratory findings and a magnetic resonance imaging which revealed a mass in the right adrenal gland. The tumorous mass in the right adrenal gland was removed surgically and a total thyroidectomy was performed. Pathological findings revealed a multifocal papillary (micro)carcinoma and adrenocortical adenoma.

Conclusion: Most aldosterone-producing adenomas and papillary thyroid carcinomas are sporadic; and the association between the tumors was ruled to be most likely accidental because of no family history or genetic testing. However, while no hereditary cancer syndromes were identified in this case, this does not preclude the possibility of an untested or unknown disorder.

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