Searchable abstracts of presentations at key conferences in endocrinology
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18th European Congress of Endocrinology

Eposter Presentations

Diabetes complications

ea0041ep484 | Diabetes complications | ECE2016

Association of the PPARG2 Pro12Ala, TNFα G(308)A and G(238)A, Lipc C(-514)T, Ace I/D, Slco1b1 Val174ala polymorphism with endothelial function and atorvastatin response in type 2 diabetic patients

Lebedeva Nadezhda , Vikulova Olga , Nikitin Alexei , Shamkhalova Minara , Shestakova Marina , II Dedov

Aim: To assess the association of the endothelial dysfunction (ED) parameters and the lipid-lowering response to atorvastatin therapy in patients with T2D with genetic markers of inflammation.Methods: We include 97 T2D patients with first prescribed atorvastatin 10–20 mg: M/F 26/71; mean age 57 years. After 12 month of statin therapy, patients had fasting lipid profiles and ED parameters repeated. For ED evaluation, we performed pulse wave analysis ...

ea0041ep485 | Diabetes complications | ECE2016

Acupuncture treatment for diabetic gastroparesis

Kostitska Iryna

Introduction: The aim of this study was to compare the effectiveness acupuncture for the treatment of diabetic gastroparesis (DG). Acupuncture may improve gastrointestinal symptoms in patients with various disorders, but its efficacy in diabetic gastroparesis is unclear.Materials and methods: We have studied 23 subjects with type 2 DM with the duration of 14.2±3.1 years, with longstanding and uncontrolled carbohydrate metabolism (mean value of HbA<s...

ea0041ep486 | Diabetes complications | ECE2016

The dual burden of tuberculosis and diabetes in hospitalized Spanish patients

Duran Alejandra , Calvo Beatriz , Mendez Manuel , Ortola Ana , Crespo Irene , Marco Javier

Aims: The dual burden of tuberculosis (TBC) and diabetes (DM) has attracted much attention in the past decade. Patients with type 2 diabetes have a higher risk of developing pulmonary tuberculosis; moreover, DM co-morbidity in pulmonary TB is associated with poor treatment outcomes. Patients admitted to Internal Medicine (IM) Departments are an ideal setting to analyze the prognostic roll of DM on TBC clinical course.Material and method: The Minimum Basi...

ea0041ep487 | Diabetes complications | ECE2016

Improvement of finger amputation technique in the treatment of diabetic foot

Prystupiuk Maksym , Onofriichuk Iuliia , Naumova Liudmyla , Prystupiuk Lev , Naumova Marianna , Prystupiuk Oleksandr

Introduction: Diabetic foot is one of the leading disabling chronic complications of diabetes. From 40 to 60% (and in some regions up to 90%) of all non-traumatic amputations are performed in patients with diabetes. According to international epidemiological studies, the incidence of amputations reaches 206 cases per 100 thousand. In Ukraine in 2015, up to 2656 lower limb amputations were performed in patients with diabetes, which is 0.62 persons per 10 000 of population.<...

ea0041ep488 | Diabetes complications | ECE2016

Does type 2 diabetes mellitus affect bone mineral density?

Sarmadi Payam , Bazrafshan Behnaz , Bazrafshan Hamidreza , Stalla Gunter , Aghaei Mehrdad , Shadpourdashti Hossien , Mousavi Fatemeh , Eftekharie Mamak

Introduction: The effects of diabetes mellitus (DM) on bone mineralization and osteoporosis is not well established. While reduction in bone mineral density in patients with type 1 diabetes is almost confirmed, effects of type 2 diabetes on bone health is still unclear. However in some studies bone mineral density (BMD) was suggested to be normal or elevated, epidemiological reports have shown an increased risk of fracture among patients with type 2 diabetes. This paper tries ...

ea0041ep489 | Diabetes complications | ECE2016

Risk factors for mortality in elderly diabetic patients with pneumonia

Kocoglu Hakan , Okuturlar Yildiz , Sayilan Samet , Ozkan Hanise , Yilmaz Deniz , Ganglaliyeva Kamala , Demir Esra , Utku Irem Kirac , Hursitoglu Mehmet , Harmankaya Ozlem , Kumbasar Abdulbaki

Introduction: In this study we aimed to examine the risk factors associated with mortality of pneumonia among diabetic seniors in Turkish general population.Material and methods: After excluding individuals from other minorities, elderly diabetic patients who had been hospitalized due to pneumonia in recent three years consisted of study population. A total of 610 subjects aged 65 years or older were retrospectively analyzed and 196 patients who had no m...

ea0041ep490 | Diabetes complications | ECE2016

Mauriac syndrome – a rare type 1 diabetes mellitus complication and an opportunity for intervention

Souteiro Pedro , Belo Sandra , Costa Maria Manuel , Carneiro Fatima , Carvalho Davide

Introduction: Mauriac Syndrome is characterized by the presence of hepatomegaly, growth retardation, delayed puberty and cushingoid features. This entity is traditionally diagnosed during the work-up of hepatic enzymes alterations in children/young adults with type 1 diabetes mellitus (T1DM) with poor glycaemic control. However, the impact of metabolic control in the normalization of hepatic analytic profile is not clarified.Methods and design: Retrospec...

ea0041ep491 | Diabetes complications | ECE2016

The incidence of sleep apnea in patients with type 1 diabetes

Darashkevich Ina , Mokhort Tatiana , Nikanava Lola , Tishkovsky Serhey

It is determined that sleep apnea itself can affect the level of HbA1c, thereby affecting the compensation of carbohydrate metabolism in type 2 diabetes.Objective: To determine the quantity and type of sleep apnea in diabetes type 1, depending on the level of HbA1c.Materials and methods: The study involved 50 people with type 1 diabetes without the presence of diabetic autonomic neuropathy or diseases of the pulmonary system and EN...

ea0041ep492 | Diabetes complications | ECE2016

Usefulness of plasma glucose concentration to HbA1c ratio in predicting clinical outcome during acute illness with extremely hyperglycemia

Su Yu-Wen , Hsu Chien-Yi , Chen Harn-Shen

Background: Stress induced hyperglycemia is common during acute illness and is related to poorer clinical outcome.Objective: To evaluate the correlation between plasma glucose elevation from baseline and clinical outcome during acute illness.Design: Retrospective, observational cohort of patients presenting to emergency department with plasma glucose concentration >500 mg/dl.Participants: 661 patients vis...

ea0041ep493 | Diabetes complications | ECE2016

The influence of glycemic control on bone mineral density and bone metabolism in patients with Type 2 Diabetes Mellitus

Barmpa Eleftheria , Karamagiolis Spyros , Tigas Stelios , Navrozidou Parthena , Vlychou Marianna , Fezoulidis Ioannis , Koukoulis Georgios N , Bargiota Alexandra

Introduction: Although patients with type 2 diabetes mellitus (T2DM) have normal or higher bone mineral density (BMD) comparing to healthy subjects, they appear to be at high risk of osteoporotic fractures. Factors that contribute to bone fragility in T2DM are not clearly understood. The aim of this study was to evaluate the influence of glycemic control on bones in T2DM.Methods/design: We studied 40 patients with T2DM (mean age: 54.3+3.2 years, M/F: 24/...

ea0041ep494 | Diabetes complications | ECE2016

Relation of mean platelet volume with serum paraoxonase-1 activity and brachial artery diameter and intima media thickness in diabetic patients with respect to obesity and diabetic complications

Karakaya Pinar

Objective: To evaluate the relation of mean platelet volume (MPV) levels with serum paraoxonase-1 activity and brachial artery diameter and intima media thickness in diabetic patients with respect to obesity and diabetic complications.Methods: A total of 201 diabetic patients grouped with respect to obesity (obese (n=89) and non-obese (n=112) and diabetic complications (with (n=50) or without (n=150) microvascular comp...

ea0041ep495 | Diabetes complications | ECE2016

Antibiotic susceptibilities of Gram-negative bacteria as infectious agents isolated from community-acquired urinary tract infections in diabetic and non-diabetic patients

Ugur Kader , Denk Affan , Sener Selcuk Yusuf , Bal Isa Ahmet , Tartar Ayse Sagmak , Orhan Bedrettin , Donder Emir , Ozkan Yusuf

Introduction: Diabetes mellitus is a metabolic disease which causes acute and chronic complications including insulin deficiency and ineffectiveness or both its incidence is increasing every day. Urinary tract infections are more frequently seen and can lead a more aggressive course in diabetic patients when compared with the population in general. The aim of this study is to determine antibacterial susceptibilities of Gram-negative bacteria isolated from diabetic and non-diab...

ea0041ep496 | Diabetes complications | ECE2016

Diabetes and cognitive impairment

Alkan Gulin , Tanrikulu Seher , Idiz Cemile , Beser Birsu , Kalem Sukriye Akca , Satman Ilhan , Cakir Sibel , Dinccag Nevin

Introduction: Diabetic patients have an increased risk of developing dementia and cognitive impairments. DM related factors such as macrovascular and microvascular complications, glucose toxicity, hyperinsulinemia have been suggested to be involved cognitive impairment even in prediabetic stage. Our aim is to establish the relationship between insulin resistance and cognitive impairment and the effect of poorly controlled diabetes on cognitive impairment.<p class="abstext"...

ea0041ep497 | Diabetes complications | ECE2016

Cystatin C and renal function in patients with type 2 diabetes mellitus

Vasilkova Volha , Mokhort Tatiana , Zekenova Kulyash

Background: Diabetic nephropathy (DN) is a serious complication of diabetes associated with increased risk of mortality, cardiovascular and renal outcomes. Diagnostic markers to detect DN at early stage are important as early intervention can slow loss of kidney function and improve patient outcomes. The aim of our study was to evaluate the role of serum cystatin C (CysC) for early detection of kidney damages in patients with type 2 diabetes mellitus (DT2).<p class="abstex...

ea0041ep498 | Diabetes complications | ECE2016

Markers of endothelial and autonomic dysfunction in early stages of glucose intolerance and in metabolic syndrome

Dimova Rumyana , Tankova Tsvetalina , Kirilov Georgi , Chakarova Nevena , Dakovska Lilia , Grozeva Greta

Aim: The aim of the study was to evaluate sE-selectin and Endothelin-1 as markers of endothelial function and autonomic tone at early stages of impaired glucose tolerance and in metabolic syndrome (MetS).Material and methods: A total of 87 subjects - 48 females and 39 males (mean age 45.7±11.6 years, mean BMI 31.4±6.6 kg/m2), divided into three groups according to glucose tolerance: 35 with normal glucose tolerance (NGT), 35 with pre...

ea0041ep499 | Diabetes complications | ECE2016

Androgenic state in patients with diabetes mellitus type 1 and diabetic nephropathy

Vaschenko Elena , Mokhort Tatjana

Objective: To analyze correlation between the duration of diabetes mellitus (DM), renal function and androgenic state indicators in patients with DM type 1.One hundred and sixty three males with DM 1 type in the age of 18–55 years (39.75±9.69) with the duration of disease more than 1 year were examined. The control group included 25 almost healthy males in the age 21–41 years (34.60±7.80). The compensation of DM was estimated by the l...

ea0041ep500 | Diabetes complications | ECE2016

Audit of management of cystic fibrosis related diabetes mellitus in Nottingham University Hospital

Yahia Seifeldin , Liew Kok Kee , Mahendra Pramya , Paszkiewicz Adrian , HLA Tun Win , Kalk William , Clayton Andy , Dewar Jane

Introduction: Patients with Cystic fibrosis are now living longer due to advances in nutritional and medical care. As a consequence a larger number are developing related co-morbidities such as cystic fibrosis related diabetes (CFRD). CFRD is the most common co-morbidity in CF, with the prevalence being up to 50% by the age of 30.Aims: To assess current practice in relation to the UK CF Trust guidelines 2004 – Screening for CFRD should begin at age ...

ea0041ep501 | Diabetes complications | ECE2016

Observational and retrospective study to analyze the changes in lipid and glycemic profiles in patients with metabolic syndrome after treatment with statins: ESMET study

del Canizo-Gomez Francisco Javier , Guinea-Lopez Rosario

The diabetogenic risk associated with statin therapy is higher in patients with pre-existing risk factors, such as metabolic syndrome (MS).Objective: To assess changes in lipid and glycemic profile in dyslipidemic subjects with MS after statin therapy.Methods: Observational, retrospective, multi-center study, conducted in 40 endocrinology Spanish hospitals. Each endocrinologist included the first 10 patients >18 years with MS, ...

ea0041ep502 | Diabetes complications | ECE2016

Assessment of dermatological conditions in diabetic patients, associations with demographic values and metabolic compensation

Kramica Ksenija , Ruza Ieva

Introduction: Diabetes mellitus (DM) is a group of metabolic diseases where prolonged hyperglycemia provoke damaging impact on internal organs and the skin as well. Comprehension of dermatological changes in DM, association with demographic values, metabolic compensation level (HbA1C) could help to define groups where skin complications may develop more often. That could be a useful criteria to diagnose DM earlier.Aim: To determine prevalence of skin pat...

ea0041ep503 | Diabetes complications | ECE2016

Investigational study of the impact of diabetes on cognitive function

Mousiolis Athanasios , Kazakos Kyriakos , Giavropoulou Maria , Gioka Mara , Kotsa Kalliopi

Introduction: Modern research studies reveal a negative impact of diabetes on cognitive function. Nonetheless, little is known about the risk factors that are involved in this disturbance. The present study aimed to examine the associations among cognitive/emotional functions and a number of metabolic factors associated with diabetes, in order to identify a possible link between cognitive decline and diabetes.Materials and methods: One hundred thirty fiv...

ea0041ep504 | Diabetes complications | ECE2016

Abstract withdrawn....

ea0041ep505 | Diabetes complications | ECE2016

Left ventricular hypertrophy and diabetic nephropathy; factors that influencing this relationship

Nelaj Ergita , Gjata Margarita , Sadiku Edite , Tase Mihal

Introduction: The prevalence of left ventricular hypertrophy (LVH) is high among patients with chronic kidney disease (CKD) and associated with a lower cardiac functional status, particularly in patients with diabetes mellitus (DM). The aim of the study was to estimate prevalence of LVH and to define factors influencing to development of LVH in patients with diabetic nephropathy (DN).Methods: patients with type 2 DM were studied - 22 males, 43 females, m...

ea0041ep506 | Diabetes complications | ECE2016

Estimation of the frequency of nighttime hypoglycemic reaction cases in diabetes maelicus of the Type 1

Makhlina Elena , Mokhort Tatyana , Navmenova Yana , Savasteeva Irina

Objective: To estimate the frequency of night time hypoglycemic reaction cases in daily monitoring of the glucose in interstitial fluid under the conditions of DM 1.Materials and methods: The study of daily glucose dynamics was conducted with the use of the continuous glucose monitoring system made by the company Medtronik Minimed, USA. The study included 113 patients with DM 1. Patients ware divided into 2 groups: group 1 with hypoglycemic reaction case...

ea0041ep507 | Diabetes complications | ECE2016

The diabetic hand: a forgotten complication

Samir Merad Mohamed , Benziane Zakaria , Mohammedi Fatiha , Benouis Amina

Background and aims: The diabetic hand infection is less reported in the literature. Therefore, it is easily ignored and underestimated resulting in increased morbidity among the diabetic population. The aim is to determine the clinical and therapeutic characteristics in our hospitalized patients.Materials and methods: All hand infection patients admitted to the Department of Diabetes and Endocrinology at Oran University Hospital center during 10 years w...

ea0041ep508 | Diabetes complications | ECE2016

Improvement of specialised help to patient with diabetic foot syndrome in Uzbekistan

Ibragimova Nilufar , Kamalov Telman , Shakirov Hamidulla , Kokareva Lyudmila , Platonova Oxana

Goal: Decrease a number of lower limb amputations in PDM in Uzbekistan by improvement of specialised help given to patients with DFS.Materials and methods: Prior to 2010 there were only 2 ‘Diabetic foot’ rooms in Tashkent, Uzbekistan. In 2010–2012, ‘UMID’ association jointly with Uzbekistan Ministry of Health and Research Centre for Endocrinology implemented a project ‘Prevention of lower limb amputations in people with diab...

ea0041ep509 | Diabetes complications | ECE2016

Risk factors for fetal macrosomia in gestational diabetes

Bukelskiene Zivile , Naskauskiene Gintare , Visockiene Zydrune

Background: A fetal macrosomia is the most frequent complication of gestational diabetes mellitus (GDM) in Lithuania. The aim of our study was to assess the predicting factors of fetal macrosomia in GDM.Methods: Retrospective data analysis of 3 547 women who delivered in Vilnius University Hospital Santariskiu Klinikos in 2015 was performed. Documented GDM risk factors were obtained from medical records and electronic database. Newborns over 4000 g birth...

ea0041ep510 | Diabetes complications | ECE2016

Stroke recurrence (but not mortality) is higher among diabetic and prediabetic patients

Silva-Fernandez Julia , Garcia-Ruiz Rafael , Garcia-Ruiz Rosa M , Carmen Blanco-Valero M , Gonzalez-Pereira Carolina

Introduction: Diabetes Mellitus (DM) and prediabetic states (pre-DM) are well known risk factors for stroke. Admission blood glucose level and its control during hospital stay, help predicting arterial recanalization after thrombolysis and middle and long term prognosis. We analysed recurrence, mortality and nosocomial infectious complications in DM, pre-DM and patients without previous or newly diagnosed DM or pre-DM.Methods: Descriptive analysis in con...

ea0041ep511 | Diabetes complications | ECE2016

Clinical factors and severity of diabetic foot infection according to the PEDIS classification

de Sousa Lages Adriana , Oliveira Patricia , Queiros Susana , Guelho Daniela , Cardoso Luis , Vicente Nuno , Martins Diana , Oliveira Diana , Ventura Mara , Carrilho Franscisco

Introduction: The complications related to ulcerated foot lesions are a common cause of hospitalization among diabetics. Diabetic foot infection is associated with high morbidity and is the most common precipitating factor to precede amputations of the lower limbs.Methods: Retrospective, cohort study; were included 200 patients from the Diabetic Foot consultation of the Endocrinology Department between 1 January and 31 August 2015. Ulcerated lesions were...

ea0041ep512 | Diabetes complications | ECE2016

Sympathetic dysfunction in patients with diabetes revealed by task force monitor

Nisic Tanja , Stojanovic Milos , Ilic Miroljub , Gostiljac Drasko , Popovic Srdjan , Stojkovic Mira , Beleslin Biljana , Savic Slavica , Barac Marija , Lalic Tiana , Ciric Jasmina , Zarkovic Milos

Introduction: It is common that patients with diabetes have a dominant parasympathetic dysfunction.Aim: Assessing the function of the autonomic nervous system in diabetic subjects.Methodology: Task force monitor was used for testing at rest and passive orthostasis evaluating baroreceptor sensitivity (BRS), spectrum variability of RR-interval of high frequencies HF RRI which is linked to the parasympathetic, low frequency variabilit...

ea0041ep513 | Diabetes complications | ECE2016

Bad eating habits among type II diabetic patients at tertiary hospital: a case-control study

Mansoury Mohammed , Al Zaydi Mohammed , Alwan Ali , Alhusuny Ameer

Background: There is a strong association between type II diabetes mellitus (DM) and gaining weight. Lifestyle modification is an important factor for weight management to overcome the obesity as well as DM epidemics.Aim of study: To find the differences of eating habits and Rosenberg Self-Esteem between DM patients and control and to find the strongest contributor of risk factors by study groups.Methods: A hospital-based matched c...

ea0041ep514 | Diabetes complications | ECE2016

Assessment of neutrophil gelatinase-associated lipocalin in diabetic patients

Sazonava Alena , Mokhort Tatiana , Shyshko Volha , Mokhort Alena , Shishko Elena

Background: Diabetic nephropathy (DN) is a major cause of morbidity and mortality in type 1 diabetes (T1D) patients and associated with increased cardiovascular risk in type 2 diabetes (T2D) patients. Early detection of DN using neutrophil gelatinase-associated lipocalin (NGAL) assessment can help to reveal predisposed patients to its progression and to prevent progression of DN. Especially important it is in patients with normoalbuminuria.Aim: To determ...

ea0041ep515 | Diabetes complications | ECE2016

Hydroxyvitamin D status and it is relation to some cardiovascular risk factors in Egyptian female patients with type 2 diabetes

Hassan Zeinab , Abaza Dina , Saed Mohamed , Hassan Inass

Introduction: Recent observational evidence suggests strong links between low vitamin D levels and a range of cardiovascular risk factors, including hypertension, diabetes, obesity and hyperlipidemia. In addition increased rate of all-cause and cardiovascular mortality.Objectives: To determine 25-hydroxyvitamine D (25(OH) D) levels as well as its relationship with some cardiovascular risk factors among Egyptian Female patients with type 2 diabetes.<p...

ea0041ep516 | Diabetes complications | ECE2016

Assessment of quality of life in anemic and non-anemic patients with early stages of diabetic nephropathy

Pchelin Ivan , Shishkin Alexander , Erman Mikhail , Vasilkova Olga

Aims: Anemia occurs early and predicts high risk of cardiovascular events and death in patients with diabetic nephropathy. The aim of this study was to assess the influence of anemia on the quality of life of patients with early diabetic nephropathy.Methods: We investigated 95 anemic and 32 non-anemic patients with type 2 diabetes mellitus and early diabetic nephropathy (CKD stages 1–3). Anemia was defined according to WHO criteria. Anemic patients ...

ea0041ep517 | Diabetes complications | ECE2016

Macular pigment optical density in type 2 diabetes and normal controls: correlation with vitamin D levels

Bayraktar Bilen Neslihan , Koseoglu Derya , Demir Onal Eda , Kalayci Defne , Berker Dilek

Aim: To compare macular pigment optical density (MPOD) in diabetic and non-diabetic patients by using heterochromatic flicker photometry and to investigate the correlation of MPOD with glycosylated hemoglobin (HbA1C), serum lipid levels and vitamin D levels.Methods: Sixty-seven patients with 10/0 visual acuity were divided into group 1 (controls, n: 35) and group 2 (diabetics without retinopathy, n: 32). MPOD was measured with a heteroc...

ea0041ep518 | Diabetes complications | ECE2016

Vitamin D deficiency association with microvascular complications in type 1 diabetic patients

Prakapiene Edita , Kondrotiene Aiste , Kreivaitiene Egle , Miezyte Raminta , Bauraite Karolina , Radzeviciene Lina , Verkauskiene Rasa

Introduction: Low levels of vitamin D are commonly found in people with type 1 diabetes and recently studies found that vitamin D deficiency (VDD) contributes to the risk of developing diabetic microvascular complications. The aim was to determine the relationship between microvascular complications of diabetes and 25-hydroxyvitamin D (25(OH)D) levels in type 1 diabetic patients.Methods: A total of 143 adults (60 male and 83 female) with type 1 diabetes ...

ea0041ep519 | Diabetes complications | ECE2016

Diabetes mellitus type-II related hypertension and cardiovascular diseases: involvement of impaired regulatory renin-angiotensin-aldosterone system

Shakoor Shamila , Kokab Raja Ghazala , Jahan Sarwat , Raza Abida , Akram Maleeha , Ali Raza Kazmi Syed , Nazir Sidrah , Ahmed Naseem Afzaal , Qayyum Mazhar , Shakeel Raza Rizvi Syed

Diabetes mellitus type-II (DM-2) is a metabolic disorder characterized by high blood glucose levels due to insulin resistance and relative insulin deficiency. DM-2 often leads to hypertension, a prolonged condition of elevated blood pressure (BP). Both hypertension and diabetes have a pathological role in causing cardiovascular diseases (CVDs). While renin-angiotensin-aldosterone system (RAAS) regulates arterial BP, any pathology in RAAS system may lead to hypertension and rel...

ea0041ep520 | Diabetes complications | ECE2016

Frequency of occurrence and factors of diabetic retinopathy advancement in people with DM type 2 in Uzbekistan

Normatova Nargiza , Ibragimova Nilufar

Goal: To study a frequency of occurrence and factors of progressive diabetic retinopathy (DR) in people with DM type 2 in Uzbekistan.Materials and study methods: Within the framework of WDF project ‘Prevention of blindness in people with diabetes mellitus in Uzbekistan’ granted to ‘UMID’ association in 2008, we carried out DR screening in people with DM type 2 in three pilot regions of Ferghana, Bukhara areas and the Republic of Karak...

ea0041ep521 | Diabetes complications | ECE2016

Determinants of diabetic retinopathy in Moroccan type 2 diabetic patients: which glycosylated haemoglobin threshold?

Baki Salwa , El Mghari Ghizlane , El Ansari Nawal

Background: Diabetic retinopathy represents a major cause of the blindness worldwide. A variety of risk factors has been identified in several population, but to date, comprehensive data concerning our particular risk factors are lacking. The aim of the study was to determine the risk factors of diabetic retinopathy in Moroccan type 2 diabetic patients and to determine the threshold of HbA1c predicting retinopathy.Materials and methods: All patients 18 y...

ea0041ep522 | Diabetes complications | ECE2016

Waist circumference is a predictive factor for cardiovascular disease in diabetic patients

Nelaj Ergita , Gjata Margarita , Tase Mihal

Introduction: Obesity worsens the prognosis of diabetic patients by increasing the cardiovascular risk and chronic complications. Waist circumference, as a brief indicator of visceral obesity, is associated with multi-metabolic disorders and cardiovascular diseases. The aim of the study was to report the prevalence of WC in individuals with diabetes and find out their association with other cardiovascular risk factors.Material and Methods: We performed a...

ea0041ep523 | Diabetes complications | ECE2016

Risk factors of diabetic cardiac autonomic neuropathy in patients with insulin dependent diabetes mellitus: a meta analysis

Dafaalla Mohamed , Nimir Mohammed , Mohamed Mosab , Ali Omer , abdalrahman Ihab

Objectives: We aimed to stratify the possible risk factors for diabetic cardiac autonomic neuropathy (CAN).Methods: We did a metaanalysis of risk factors of CAN. We did a web based search for literature in MEDLINE/PubMed, SCOPUS database, and CENTRAL database up to August 2015. We included clinical trials or cohort studies that provide data about relationship between CAN and variables of interest. Our risk factors of interest were age, sex, duration of d...

ea0041ep524 | Diabetes complications | ECE2016

Is there a tendency for thrombosis in gestational diabetes mellitus?

Gorar Suheyla , Alioglu Bulent , Ademoglu Esra Nur , Uyar Seyit , Bekdemir Handan , Candan Zehra , Saglam Beylan , Koc Gonul , Culha Cavit , Aral Yalcin

Aims: Impact of gestational diabetes mellitus on the coagulation system, dynamics involved at a pathophysiological level and the exact mechanism remain unclear.To evaluate association between diabetes-related parameters and haemostatic factors in order to search for a tendency of thrombosis in gestational diabetes mellitus.Methods and Material: Nineteen pregnant women who had gestational diabetes mellitus, 16 healthy pregnant and 1...

ea0041ep525 | Diabetes complications | ECE2016

Analysis of disability in population due to diabetic ophthalmopathy

Djamalova Shirin , Iskandarova Shakhnoza

Introduction: Among the complications of diabetes ophthalmic are among the most severe. Uzbekistan’s population is over 30 million people; according to statistics the number of diabetes patients is 130 000 people, but the real number is at least six times bigger - more than 800 000 (WHO). Our study aimed to investigate the disability features due to ocular complications of diabetes in Tashkent within 10 years.Methods: Data of examinations in special...

ea0041ep526 | Diabetes complications | ECE2016

Diabetic muscle infarction in a 54-year-old female: a case report

Lumi Ema , Puca Entela , Dyrmishi Blertina , Bitri Sonila , Puca Edmond , Pengo Petrika , Ylli Agron

Introduction: Diabetic muscle infarction is a very uncommon complication of diabetes and predominately occurs in type 1 diabetes (70% of cases) or long standing poorly controlled type 2 diabetic patients, often misdiagnosed as cellulitis. It is defined as spontaneous ischemic necrosis of skeletal muscle that is unrelated to atheroembolism or occlusion of major arteries.Case presentation: We report a case of 54-years-old women non-smoker with an 8 years h...

ea0041ep527 | Diabetes complications | ECE2016

Detection of hypoglycemia in type 2 diabetic patients

Tsirona Sofia , Pappas Christos , Kandaraki Eleni , Kassi Georgia , Chronopoulou Genovefa , Diamanti-Kandarakis Evanthia

Introduction: Hypoglycemia consists a significant problem in insulin treated type 2 diabetic patients. The present study compared the incidence of hypoglycemic episodes in type 2 diabetics between continuous glucose monitoring/CGM vs self monitoring of blood glucose/SMBG.Methods: Seventeen patients with type 2 diabetes underwent a 24 h CGM for a period of 3–5 consecutive days. At the same period they recorded their glucose values using SMBG from fou...

ea0041ep528 | Diabetes complications | ECE2016

Diabetes mellitus, pre-dialysis, extreme anxiety, and sarcoidosis

Shah Usman , Soule Erik , Nikookam Yasmin , James Ajit , Casey Edel , Nikookam Khash

Diabetic nephropathy is the leading cause of chronic kidney disease and is responsible for 30–40% of all end stage renal disease (1). Where there is rapid decline in eGFR, we should also consider other aetiologies.This is the case of a 65-year-old Caucasian gentleman with complex presentation and novel management strategy with type 2 diabetes mellitus since 1999 which was effectively managed, evident by reasonable control of HBA1c; Pharmacotherapy r...

ea0041ep529 | Diabetes complications | ECE2016

Good renal and vital prognosis of metformin induced Lactic acidosis

Casel Antoine , Memain Nathalie , Gambier Nicolas , Verdiere Bruno , Cohen Regis

Metformin Associated Lactic Acidosis (MALA) is defined by a Ph <7.35 and lactate levels greater than 5 mM. It must be distinguished from other lactic acidosis usually secondary to septic shock. Renal functional prognosis and mortality are not clearly separated in publications and many make the amalgam between the two entities with an estimated mortality of 30 to 50% and poor renal prognosis.We did a retrospective, observational, cohort study of patie...

ea0041ep530 | Diabetes complications | ECE2016

A rare case of acute renal failure: rhabdomyolysis due to hyperosmolar hyperglycemic state

Genc Tugrul Burak , Okuturlar Yildiz , Kocoglu Hakan , Sayilan Samet , Inan Yesim Ozdem , Erdogan Ezgi , Mert Meral , Erismis Betul , Ozdemir Bahar , Harmankaya Ozlem , Kumbasar Abdulbaki

Introduction: Rhabdomyolysis is usually attributed to trauma. However, there is an association of rhabdomyolysis with hyperosmolar states. It is also important to realize that hyperosmolar coma can be the presenting complaint of a diabetic seeking medical attention for the first time. In this case-report we aimed to present a patient with acute kidney injury due to rhabdomyolysis and hyperosmolar state.Case report: Forty nine-year-old black male patient ...

ea0041ep531 | Diabetes complications | ECE2016

Clinical profile of type 2 diabetic patients suffering of erectile dysfunction

Omri Marwa , Ounaissa Kamilia , Brahim Asma Ben , Abid Abdelmajid

Introduction: The number of patients with diabetes has been increasing at an alarming pace for the last decade. Sexuality is frequently affected in diabetic patients.The aim of this study was to describe the clinical profile of a group of type 2 diabetic patients suffering of erectile dysfunction (ED).Methodology: This was a cross-sectional study involving a population of 70 type 2 diabetic patients recruited from the day hospital ...

ea0041ep532 | Diabetes complications | ECE2016

Diabetic papillopathy with macular edema treated with intravitreal ranibizumab

Kim Moosang

Introduction: We report a case of diabetic papillopathy that demonstrated a resolution of optic disk swelling and rapid visual recovery when intravitreal ranibizumab was administered.Case report: A 51-year-old male presented with acute painless visual loss in his right eye. His vision was 20/320 in the right eye and 20/50 in the left eye. Fundus examination of the right eye showed nonproliferative diabetic retinopathy with macular edema and a swollen opt...

ea0041ep533 | Diabetes complications | ECE2016

Diabetes and rhino-orbito-cerebral mucormycosis

Matta-Coelho Claudia , Silva Diana , Carvalho Sofia Daniela , Amorim Jose , Monteiro Ana Margarida , Souto Selma B , Marques Olinda

Introduction: Rhino-orbito-cerebral mucormycosis is a rare invasive fungal infection more common in diabetic and elderly patients. The presentation is acute, severe and rapidly progressive to disseminated infection. The diagnosis is done by the identification of risk factors, clinical and radiologic signs and tissue biopsy consistent with mucormycosis. The mortality rate is high, so timely diagnosis and intervention lead to better outcomes.Clinical case:...

ea0041ep534 | Diabetes complications | ECE2016

Lipemic diabetic ketoacidosis as a presentation of type 1 diabetes mellitus

Doraiswamy Amudha , Henry Adelyn

Introduction: Diabetic ketoacidosis (DKA) is a complication of insulin deficiency and can rarely be associated with diabetic lipemia, which is a life threatening condition.Case report: We report a 20-year-old male, who visited emergency department with a short history of abdominal pain and vomiting. Clinically he was alert, had kussmaul’s breathing, and was found to be hyperglycaemic, with metabolic acidosis and ketonemia (RBS 18, Ph 7.18 HCO3 8.4)....

ea0041ep535 | Diabetes complications | ECE2016

Diplopia as a presenting symptom of diabetes mellitus

Unsal Yasemin Aydoğan , Efe Fatma Kaplan , Deveci Selcen , Beyan Esin , Morkavuk Gulin , Altay Mustafa

Introduction: The neuropathies are one of the most common complications seen in diabetes, affecting up to 50% of diabetic patients. Isolated or combined paralysis of 3rd, 4th and 6th cranial nerve can be seen.Case presentation: Sixty-six-year-old male patient was admitted to the neurology department with the complaints of diplopia persisting for 15 days. Cranial images revealed no abnormal findings. Patient was directed to internal medicine clinic due to...

ea0041ep536 | Diabetes complications | ECE2016

The presence of risk factors for type 2 diabetes and glucose tolerance in pregnant women

Mladenovic Violeta , Djukic Aleksandar , Macut Djuro

Background: Pregnancy is a state of insulin resistance that can predict diabetes development in some women, and is associated with increased risk for neonate and for mother. Frequency of glucose intolerance may be increased in the follow-up years.Aim: The aim of this study is to determine the presence of risk factors for type 2 diabetes and degree of glucose tolerance in population of pregnant women.Materials and methods: The study...

ea0041ep537 | Diabetes complications | ECE2016

Calculator for myocardial infarction risk in patients with type 2 diabetes mellitus

Takhirova Feruza , Akbarov Zairkhodja

Study was initiated to perform integral assessment of myocardial infarction (MI) risk in patients with type 2 diabetes mellitus with genetic markers taken into account as well as to develop a method for its prediction in this category of patients. As to relative risk of factors causing MI in Uzbek patients with type 2 diabetes mellitus, myocardial infarction in family medical history comes the first followed by left ventricular hypertrophy, age, ACE gene DD genotype, arterial ...

ea0041ep537b | Diabetes complications | ECE2016

Renal function reserve state in patients with diabetic kidney disease

Kuznetsova Kateryna

Kidneys reserve mechanisms are of great scientific and practical interest.In 56 patients with diabetes mellitus two types and diabetic kidney disease (DKD), 24 men (42.9%) and 32 women (57.1%) aged from 38 to 81 years (61.3±2.65) had been estimated the renal functional reserve (RFR) with water-salt load of 0.5% NaCl in the amount of 0.5% body mass to determine the reduction of nephron’s amount using the level of glomerular filtration rate (GFR)...