Endocrine Abstracts

Cigarette smoke contains over 60 well established carcinogens. There are strong links between some of these carcinogens and various types of smoking-induced cancers. In this study we investigated whether cigarette smoke extracts (CSEs) affects the cell proliferation, migration, and invasion of BG-1 human ovarian cancer cells by alteration of epithelial-mesenchymal transition (EMT). We confirmed that CSEs increased the ovarian cancer cell viability in a dose-dependent manner. A...

Introduction: Environmental toxins, including those deriving from illegal and hazardous disposal of urban and chemical waste, are known to act as endocrine disruptors and to increase the risk of malignancy and cancer mortality. The present study aimed at investigating prevalence and characteristics of thyroid diseases in the area of Acerra, a town in the perimeter of the so called ‘Land of Fires’.Methods: The screening included subjects aged &#...

Introduction: Obesity is a global health problem. More than half (54%) of the adult population in Serbia and 58.5% of adult population in the north province, Vojvodina is obese or overweight. Hence, it is urgent to identify environmental factors which may contribute obesity. Bisphenol A (BPA) is one of the most extensively used chemical in production of food and beverage containers, epoxy resins, polycarbonate plastics and well known endocrine disruptor. The aim of this study ...

Placenta exchanges vital factors including oxygen, carbon dioxide, cation (copper, iron, calcium) and glucose that are essential to fetal growth. Copper, iron, calcium cation and glucose transfer genes are regulated by reproduction-related hormones, vitamin D and human placental lactogen. These molecules are transferred by specific receptors located on cell membrane or cytoplasm in placenta. These substances disturb action of reproduction-related hormones (ex> estrogen, pr...

Synthesized chemicals that not existed in the environment have been troubled endocrine physiology. These endocrine disruptors (EDs) had been noted and replaced with other chemicals. Most of compound banned for production act as an estrogen. But other than estrogen, especially thyroid hormone related EDs are noted for early brain and neural development. Brominated flame retardants (BFRs) are representative known as thyroid disruptor because of its structural similarity. 2,4,6-t...

Introduction: Endocrine disruptor compounds (EDCs) are chemicals that may interfere with the endocrine system and produce adverse developmental, reproductive, neurological and immune effects.These agents can be found in household, in the industry and in our environment.Endocrine disruptors are substances that interfere with the synthesis, secretion, transport, binding, action, or elimination of natural hormones in the body that are responsible for development, behavio...