Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 43 | WCTD2016 | Next issue

World Congress on Clinical Trials in Diabetes

Abstract Topics

Meta-Analysis of Phase 2/3 Studies

ea0043oc31 | Meta-Analysis of Phase 2/3 Studies | WCTD2016

Do mobile phone applications improve glycemic control in the self-management of diabetes: A systematic review, meta-analysis and GRADE of 14 RCTs

Carter Ben , Hou Can , Hewitt Jonathon , Francisa Trevor , Mayor Sharon

Background: Diabetes mobile phone applications (hereafter referred to as diabetes apps) are a promising tool for self-management. Due to the ubiquitous, low cost, interactive and dynamic health promotion, and there is potential for a cost-effective intervention in diabetes self-care. However, there is uncertainty of the clinical effectiveness.Objectives: To investigate the effect of mobile phone applications on glycemic control in the self -management of...

ea0043oc32 | Meta-Analysis of Phase 2/3 Studies | WCTD2016

Cohort Analysis of Randomized Clinical Trials on long acting GLP-1 receptor agonists versus DPP4 inhibitors

Pham Thuy , Singh Mukunda , Dao Marvin , Herrera Griselda , Asuncion Katherine

Background: Oral semaglutide GLP1 receptor agonist is coformulated for better absorption compared to prior injectable semaglutide. Phase 2 open label, dose escalation randomized clinical trials of semaglutide and liraglutide investigating the dose-response relationship between the two. DPP-4 inhibitor produces a smaller glycemic reduction and minimal weight reduction through effect of endogenous GLP-1 receptor activity, while GLP-1RAs yield greater efficacy related to the phar...

ea0043oc33 | Meta-Analysis of Phase 2/3 Studies | WCTD2016

Daytime napping, daytime sleepiness and the risk of metabolic diseases: dose-response meta-analysis

Yamada Tomohide , Shojima Nobuhiro , Yamauchi Toshimasa , Kadowaki Takashi

Background: Adequate sleep is important for good health, but it is not always easy to achieve because of social factors. Daytime napping is widely prevalent around the world. We recently published a meta-analysis, in which a J-shaped relationship was identified between naptime and cardiovascular diseases.Objective: In this research, we also performed a meta-analysis to investigate the association between daytime sleepiness or napping and the risk of meta...