Endocrine Abstracts

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Thyroid hormones play crucial roles in foetal growth and neurodevelopment which are dependent on adequate supply of maternal thyroid hormones from early gestation onwards. During pregnancy there are important physiological changes resulting in altered reference ranges and complicating the interpretation of thyroid function tests. Thyroid dysfunction is common in pregnancy and the prevention of adverse obstetric and foetal outcomes relies upon careful monitoring and treatment b...

Endocrinologists are faced with three main issues when managing a woman with a prolactinoma contemplating pregnancy: restoration of fertility, consideration of the effects of dopamine agonists on the developing foetus, and the effects of the high oestrogen environment of pregnancy on prolactinoma expansion. Untreated hyperprolactinaemia leads to anovulatory menstrual cycles with resultant amenorrhoea and infertility in most patients. Therefore, treatment is usually required in...