Searchable abstracts of presentations at key conferences in endocrinology
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44th Meeting of the British Society for Paediatric Endocrinology and Diabetes

Oral Communications

Oral Communications 4- CME

ea0045oc4.1 | Oral Communications 4- CME | BSPED2016

The clinical utility of Co-peptin measurement in paediatric endocrine practice

Punniyakodi Sadhanandham , Cheetham Timothy , Alins-Sahun Yolanda , Gray Susan

Background: Arginine Vasopressin (AVP) measurement is difficult. When available there has historically been a lengthy interval between sampling and a result. Co-peptin is a 39 amino-acid glycopeptide that is derived from a pre-prohormone consisting of AVP, neurophysin II and co-peptin. It is released in an equimolar ratio with AVP into the circulation. Co-peptin is stable and can be used as a surrogate marker of AVP release in hyper and hypo-osmolar disorders. Many laboratorie...