Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology Endocrine Update 2017

Obesity Update

Oral Communications

ea0048oc1 | Oral Communications | SFEEU2017

Which test should the bariatric physician use to test for postprandial hypoglycaemia – prolonged oral glucose tolerance test versus mixed meal test?

Tharakan George , Behary Preeshila , Al-Najim Werd , Chahal Harvinder , Miras Alexander , Ahmed Ahmed , Bloom Stephen , Tan Tricia

Background: An increasingly recognized complication of Roux-en-Y Gastric Bypass (RYGB) surgery is the development of postprandial hypoglycaemia (PPH). However, there remains no agreed standard on how to diagnose this condition. Commonly used tests include a prolonged oral glucose tolerance test (POGTT) and mixed meal tolerance test (MMTT). Little is known regarding how these tests compare in the post-bariatric population.Methods: Ten patients who had con...

ea0048oc2 | Oral Communications | SFEEU2017

Cardiac risk stratification in bariatric patients: a step to minimise heartache

Younus Hafsa , Sharma Amit , Majid Kiran , Sarma Diwakar , Chakravartty Saurav , Patel Ameet G.

Introduction: Morbid obesity has serious associated co morbidities and is an independent risk factor for ischaemic heart disease. Obesity together with low functional status and exercise tolerance makes pre-operative cardiac assessment difficult and patients with few cardiac risk factors are often referred for cardiac assessment. This can not only be burdensome to services and prolongs waiting times for surgery but can also cause patient anxiety and poor compliance.<p clas...

ea0048oc3 | Oral Communications | SFEEU2017

The early improvement of glycaemia following RYGB can be mimicked by a Very Low Calorie Diet in obese volunteers with diabetes

Behary Preeshila , Tharakan George , Al-Najim Werd , Brown Adrian , Miras Alexander , Stoenchev Kostadin , Chahal Harvinder , Purkayastha Sanjay , Moorthy Krishna , Ahmed Ahmed , Bloom Steve , Tan Tricia

Introduction: Improvement in glycaemia is observed early after Roux-en-Y Gastric Bypass surgery (RYGB) in patients with diabetes. Commonly cited mechanisms to account for these changes include the elevation of gut hormones, increase in bile acids levels, changes in the gut microbiota and calorie restriction. Calorie restriction is believed to play a role in improving hepatic insulin sensitivity and reduce hepatic glucose output early after RYGB, in the context of non-significa...

ea0048oc4 | Oral Communications | SFEEU2017

One year efficacy, safety and tolerability outcomes of endoscopic proximal intestinal exclusion therapy using the Endobarrier device: institution of the UK’s first National Health Service Endobarrier service for type 2 diabetes and obesity

Gupta Piya Sen , Yadagiri Mahender , Irwin Susan , Burbridge Wyn , Gandhi Hardeep , Alden Rachel , Bleasdale John , Fogden Ed , Anderson Mark , Ryder Bob

Introduction: Our institution leads a UK, multicentre, randomised controlled trial (REVISE-Diabesity ISRCTN00151053) investigating the interaction of Endobarrier therapy, a 60 cm endoscopically implanted proximal intestinal liner, with glucagon-like peptide-1 drug therapy.Aims: To evaluate whether acquired experience could translate into establishment of an effective and safe NHS Endobarrier service in patients with diabesity.Metho...

ea0048oc5 | Oral Communications | SFEEU2017

Copper deficiency presenting as subacute common peroneal nerve palsy post-duodenal switch surgery

Lim Jonathan ZM , Thomas Cecil

Background: Gastric reduction duodenal switch involves restrictive and mal-absorptive aspect, removing approximately 70% of stomach and most of the duodenum. Surgical alteration leading to malabsorption of macronutrients is achieved with varying results of weight loss but resulting nutritional side effects are under-recognised. Issues in nutritional complication leading to neurological complications like peripheral neuropathy are increasingly recognised. We discuss a case of s...

ea0048oc6 | Oral Communications | SFEEU2017

Complexities cause considerable confusion in confirming a case of Cushing’s (after gastric bypass surgery)

Crane James , Wierzbicki Anthony , Ramachandran Radha , McGowan Barbara

Case history: A 26 year old female with severe gastro-oesophageal reflux disease was seen in our service for assessment prior to roux-en-Y gastric bypass (RYGB) surgery for this condition. She had additional history of obesity, hypertension, insomnia, cholecystectomy for gallstones and anxiety-depression. At age 18 her weight was 85 kg, BMI 28 kg/m2. She gained 40 kg over the subsequent 8 years and in clinic was 123 kg, BMI 41.1 kg/m2 with a gynaecoid pat...

ea0048oc7 | Oral Communications | SFEEU2017

Pregnancy after bariatric surgery: a single-centre retrospective cohort study

Makaronidis Janine , Pucci Andrea , Manning Sean , Cheung Wui Hang , Kingett Helen , Buckley Grainne , Kirk Amy , Carr-Rose Kayon , Tshiala Anita , Jenkinson Andrew , Elkalaawy Mohamed , Hashemi Majid , Adamo Marco , O'Brien Pat , Richens Yana , Batterham Rachel

Background: The number of women seeking bariatric surgery in order to improve their fertility is increasing. Current guidelines recommend that pregnancy should be delayed for at least 1 year post-surgery. However, there are limited data regarding pregnancy outcomes post-surgery, particularly for sleeve gastrectomy.Methods: We performed a single-centre, retrospective cohort study of pregnancies in women post-bariatric surgery. Surgical and maternity recor...

ea0048oc8 | Oral Communications | SFEEU2017

Assessing significant risks surrounding bariatric surgery in a patient with Emotionally Unstable Personality Disorder

Tomlin Sophie

Case History: A 55 year old woman with a BMI of 57.4 was referred to our service to assess her suitability for bariatric surgery given her psychiatric surgery. Her problems with weight began aged 8 when she was sexually abused. She saw a doctor aged 14 who prescribed amphetamines for her weight, and states her problems with drugs as an adult (LSD, cannabis, amphetamines) stemmed from this. She has a diagnosis of EUPD-borderline type, and was prescribed quetiapine which had kep...