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Endocrine Abstracts (2017) 48 P14 | DOI: 10.1530/endoabs.48.P14

SFEEU2017 Obesity Update Poster Presentations (14 abstracts)

Clinical outcomes of bariatric surgery in a specialist centre

Hanaa Elkhenini1, Chris Slater2, Basil Ammori3, Basil Ammori4, Khurshid Akhtar3, Siba Senapati3, Lucinda Summers1, Lucinda Summers4, John New1, John New4, Akheel Syed1 & Akheel Syed4


1Obesity Medicine and Endocrinology, Salford Royal NHS Foundation Trust and University Teaching Hospital, Stott Lane M6 8HD, Salford, UK; 2Department of Dietetics, Salford Royal NHS Foundation Trust and University Teaching Hospital, Stott Lane M6 8HD, Salford, UK; 3Department of Bariatric and Upper GI Surgery, Salford Royal NHS Foundation Trust and University Teaching Hospital, Stott Lane M6 8HD, Salford, UK; 4Faculty of Biology, Medicine & Health, The University of Manchester, Manchester, UK.


Background: Bariatric surgery is the most successful treatment for patients with severe and complex obesity.

Aims: To assess clinical outcomes after bariatric surgery in a specialist centre.

Setting: Specialist weight management service in a university teaching hospital.

Methods: We performed an observational analysis of clinical outcomes for patients who underwent bariatric surgery during the period 31st July 2010 and 31st December 2010. All patients had assessment of their weight and body mass index (BMI), nutritional status, co-morbid conditions and medications. The results at the 36-month follow up are reported.

Results: A total of 76 patients (63 women) had bariatric surgery (61 gastric bypass, 13 sleeve gastrectomy and 2 gastric banding). The follow up rate at median 36 months after surgery was 90% (68 patients). Patients achieved significant reduction in BMI (Table 1). Significantly fewer patients were on hypoglycaemic and antihypertensive medications and continuous positive airway pressure therapy (CPAP). No changes were observed in the numbers of patients taking anti-depressants and analgesics. Levels of haemoglobin, serum iron, folate and vitamin B12 were similar or significantly higher than baseline.

Table 1 Clinical outcomes before and at median 36 months after bariatric surgery.
Outcome measuresBefore BS 36 months after BSP (Paired t-test)
Median BMI (kg/m2)5235<0.0001
Regular medicines (number of patients)(Fisher’s exact test)
Antidiabetic drugs2090.0351
Analgesics3628ns
Antihypertensives 33140.0011
Antidepressants2017ns
CPAP2750.0001
Blood results (Median)(Unpaired t- test)
Haemoglobin A1c (mmol/mol)4436<0.0001
Haemoglobin (g/L)133136ns
Serum Iron (μmol/L)10.513.50.0008
Serum Ferritin (μg/L)501130.0403
Serum vitamin B12 (ng/L)319652<0.0001
Serum folate (μg/L)6.912.1ns
CPAP, Continuous positive airway pressure therapy; ns, non-significant

Conclusion: At a median follow up of 36 months, bariatric surgery was associated with significant reduction in weight and resolution or improvement in co-morbid conditions without compromising serum levels of key micronutrients.

Volume 48

Society for Endocrinology Endocrine Update 2017

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