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Endocrine Abstracts (2017) 49 EP737 | DOI: 10.1530/endoabs.49.EP737

ECE2017 Eposter Presentations: Environment, Society and Governance Diabetes complications (2 abstracts)

Assessment of the prevalence of type 1 diabetes microvascular complications in young adults in the repablic of Belarus with regard to the duration of the disease

Yuliya Dydyshka 1 , Alla Shepelkevich 1 , Vladislav Yurkovets 1 , Elena Brutskaya-Stempkovskaya 1, & Marina Mantachik 1

1Belarusian State Medical University, Minsk, Belarus; 231th city polyclinic in Minsk, Minsk, Belarus.

Background and aims: According to current recommendations of the American Diabetes Association expedient screening of microvascular complications in all patients with type 1 diabetes (T1D) with a duration of 5 years of the disease. Therefore, the aim of study was to assess the prevalence of microvascular complications in T1D patients aged 30−45 years with regard to the duration of the disease 5−10 years and over 10 years.

Materials and methods: We examined 360 patients with type 1 diabetes, 196 (54.4%) men and 164 (45.6%) women. The average age of the patients was 37.9±4.5 (37.4−38.4) years, the age of onset of diabetes – 28.1±6.2 (27.5−28.8) years, duration of the disease – 9.0 (7.0−12.0) years, BMI – 24.8±3.95 (23.6–25.2) kg/m2, HbA1c – 8.37±1.83 (8.18−8.56). In the study, carried out a detailed clinical examination of patients with medical records analysis.

Results: Diabetic peripheral neuropathy (DPN) was diagnosed in 133 (36.9%) patients; diabetic retinopathy (DR) − 78 (21.7%) patients, diabetic nephropathy (DN) − in 146 (40.6%) patients, albuminuria was detected in 137 (38.1%) persons. In general, microvascular complications of diabetes were set at 270 (75%) patients. With increasing duration of the disease for more than 10 years showed a significant increase in microvascular complications: DPN 30.6 vs 47.1% (χ2=9.91; P=0.002); DN − 34.2 vs 50.7% (χ2=9.60; P=0.002); albuminuria − 31.9 vs 47.8% (χ2=9.06; P=0.003); DR – 40.1 vs 71.7% (χ2=34.2; P<0.005); any microvascular complications − 67.6 vs 86.9% (χ2=17.06; P<0,001). However, no significant differences in HbA1c: 8.32±1.83 vs 8.45±1.82% (P=0.539).

Conclusions: Patients with type 1 diabetes with disease duration 5−15 years microvascular complications recorded in 75% of cases. The increase in the prevalence of microvascular complications associated with the duration of the disease, but not with the level of HbA1c.

Volume 49

19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

European Society of Endocrinology 

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