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Endocrine Abstracts

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19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

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20-23 May 2017, Lisbon, Portugal Further information

Eposter Presentations: Diabetes, Obesity and Metabolism

Neuroendocrinology

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Growth hormone IGF axis - basic
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Nuclear receptors and Signal transduction

ea0049ep641 | Neuroendocrinology | ECE2017

Comparison of GHRH + arginine vs glucagon test for the evaluation of growth hormone secretion status in a cohort of adults with Prader-Willi syndrome (PWS)

Casamitjana Laia , Olga Gimenez-Palop , Raquel Corripio , Rocio Pareja , Marta Hurtado , Elisabet Gabau , Jesus Cobo , Eugenio Berlanga , Albert Cano , Lara Albert , Mercedes Rigla , Assumpta Caixas

Background: Prader-Willi syndrome (PWS) is a rare genetic disorder evolving morbid obesity and growth hormone deficiency (GHD). Testing GH-IGF1 axis is required before treatment with rhGH in adults with PWS (1). The most common used tests in these patients are GHRH+arginine (GHRH+a) and insulin tolerance test. There are no prospective data for glucagon test (GT) in comparison to GHRH+a in adults with PWS. Mechanism by which GT causes GH release remains unclear, glucagon-induce...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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