Searchable abstracts of presentations at key conferences in endocrinology
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19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

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20-23 May 2017, Lisbon, Portugal Further information

Symposia

Novel type 2 diabetes treatment: Beyond glycaemic control

ea0049s9.1 | Novel type 2 diabetes treatment: Beyond glycaemic control | ECE2017

Experimental models

Holst Jens

One of the most surprising and inspiring experimental models for type 2 diabetes therapy is gastric bypass surgery. Recent 5-year results have demonstrated massive improvements in glycaemic control and body weight, lipids and quality of life after surgery compared to intensive medical therapy (the Stampede trial). Therefore, it is imperative to identify the responsible factors with a view to utilize this knowledge for future therapy without surgery. Substantial evidence sugges...

ea0049s9.2 | Novel type 2 diabetes treatment: Beyond glycaemic control | ECE2017

Clinical studies on GLP1 - cardiovascular outcomes

Gallwitz Baptist

The incretin hormone Glucagon-like peptide-1 (GLP-1) has various non-glycaemic properties. Among those, cardiovascular effects have been described in animal studies and in clinical studies in patients with type 2 diabetes that have been treated with GLP-1 receptor agonists (GLP-1RA). In animal studies, GLP-1 and GLP-1RA have lead to a decrease in ischaemic areas in artificial myocardial infarct models. Additionally, in some clinical studies, an improvement in left ventricular ...