Endocrine Abstracts

Hyperandrogenism is a clinical condition characterized by excessive secretion of male sex hormones. An excess amount of androgens in women is manifested by symptoms of defeminization and masculinization. Hormonally active adrenal and ovarian tumors and non-tumor causes must be considered in the differential diagnosis. The authors describe the case of a 77-year-old patient who had hirsutism and reduction of the timbre of the voice. At the beginning she was suspected to have adr...

The polyglandular autoimmune syndromes (PAS) are rare disorders characterized as multiple autoimmune-mediated organ failure. PAS III includes chronic autoimmune thyroiditis with type 1 diabetes mellitus or pernicious anemia and/or vitiligo or alopecia and many other organ-specific autoimmune diseases, but never involves adrenal cortex. Several patients with PAS III and associated type 1 gastric neuroendocrine tumor (NET) have already been reported. We report probably the first...

Introduction: Life expectancy is decreased in MEN1 patients due to multiple tumors that may be larger, more aggressive, resistant to treatment and with a higher risk of recurrence.Case report: We report a 59-year-old male patient with family history of endocrine tumors (father- pituitary adenoma, son- primary hyperparathyroidism, daughter- microprolactinoma, primary hyperparathyroidism). He was first referred to our Clinic in 2007 after being incidendall...

Introduction: Insulinoma is a rare form of a functional neuroendocrine tumor with an estimated incidence at 1–2 new cases per million persons per year. This infrequent endocrinopathy, frequently escaping standard disease course, constitutes a diagnostic challenge for every endocrinologist. Successful surgical resection of the lesion is the only available method that ensures patient’s full recovery.Case study: 53 years old patient with complaint...

Introduction: Insulinomas are the most frequent cause of hypoglycemia and the most common functional endocrine pancreatic tumors. Whipple triad is often present and should alert to the diagnosis.Case report: A 36-year-old male was admitted in the emergency room with loss of consciousness, diaphoresis and blurred vision, and hypoglycemia (50 mg/dl). The patient recalled recurrent symptoms of diaphoresis, tremors and palpitations, sometimes with loss of co...