Aim: The etiology and underlying pathology of non-functional adrenal adenoma has not been clearly defined, yet. Blood pressure levels according to adrenal adenoma size has not been evaluated, yet. Therefore, we evaluated 24 hour ambulatory blood pressure levels in patients with non functional adrenal adenoma.
Materials & Methods: We studied thirty newly diagnosed adrenal adenoma patients in a tertiary health-care center. They grouped in two categories according to adenoma size. Cut-off size was taken 23 mm. 24 hour ambulatory blood pressures were evaluated in all participants. Delta blood pressure was found by calculating the difference between maximum and minimum blood pressure values.
Results: There were 17 patients with lower adenomas size, which was smaller than 23 mm, the remaining 13 patients adenomas size was equal or higher than 23 mm. Patients with higher adenomas size had statistically higher systolic delta levels compared to lower size group (70.84±34.9 to 51.29±18.0, P=0.004). Additionally; the maximume systolic (165.6±28.7 to 152.0±23.1) and maximum diastolic blood pressure (115.1±37.8 to 100.2±14.9) were higher and also minimum systolic (94.76±11.05 to 100.70±18.60) and minimum diastolic blood pressure (60.69±9.01 to 62.41±12.62) were lower in this group. However; the differences did not reach statistically significance.
Conclusion: Delta systolic blood pressure has been found toe higher in higher adenomas size group. Further studies are necessary to better clarify the association between blood pressure and non functional adrenal adenoma.
20 - 23 May 2017
European Society of Endocrinology