Endocrine Abstracts

Corticosteroid hormones are synthetized in the adrenal glands and reach many organs including the brain. Within the brain they exert their actions through mineralocorticoid (MR) and glucocorticoid receptors (GR). These receptors generally act as transcriptional regulators and change the function of brain cells in a slow manner, with effects appearing after approximately one hour. However, in the past decade it has become evident that corticosteroid receptors also change brain ...