Endocrine Abstracts (2017) 50 P225 | DOI: 10.1530/endoabs.50.P225

Peripheral neuropathy and associated factors among type 2 DM patients in FMC Abeokuta

Adewusi Titilope, Adesina Olubiyi, Alalade Boladale, Otukoya Adedeji & Olukunle Oluwale


Federal Medical Center, Abeokuta, Nigeria.


Introduction: Peripheral neuropathy is one of the common complications of diabetes and it may progress to the insensate foot at risk for ulceration. It may be evaluated for using several methods which include biothesiometry and the Michigan Neuropathy Screening Instrument. Assessment of Vibration Perception Thresholds is a validated method of screening for neuropathy while the MNSI is a two part validated screening tool for assessing peripheral neuropathy in an outpatient setting.

Aim: To determine the prevalence of peripheral neuropathy and associated factors among type 2 DM patients in FMC Abeokuta.

Settings and Design: A descriptive cross sectional study of 414 type 2 diabetics attending the outpatient clinic of FMC Abeokuta in South West Nigeria.

Methods: 414 patients were recruited using systematic random sampling method. Demographic /clinical data were documented in a questionnaire. The meaning three vpts readings was taken and values >25 volts was regarded as abnormal. The MNSI made up of fifteen ‘Yes or No’ questions on foot sensations and a brief physical examination was used. Peripheral neuropathy was defined as >/ 7 positive responses on the first part and >/ 2 points on the examination part of the questionnaire.

Statistical Analysis: Data was analyzed to determine the prevalence of peripheral neuropathy and associated factors.

Results: Prevalence of peripheral neuropathy was 65.7% and associated factors were age >65 years and diabetes duration >10 years (P<0.001).

Conclusion: The prevalence of peripheral neuropathy among outpatient type 2 diabetics in FMC Abeokuta is high. Associated factors include increasing age and diabetes duration, therefore optimal metabolic control, frequent foot screening programs for early detection and patient education is crucial for prevention of foot ulcers.

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