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Endocrine Abstracts (2017) 51 S3.1 | DOI: 10.1530/endoabs.51.S3.1

BSPED2017 Main Symposia Diabetes Track 1: Symposium 3 (2 abstracts)

Nephropathy – What have we learned from AdDIT?

David Dunger


Cambridge.


Introduction: The Adolescent type 1 Diabetes cardio-renal Intervention Trial (AdDIT) is a collaboration across 32 sites in Canada, Australia and the United Kingdom exploring the early detection and prevention of complications in adolescents with type 1 diabetes.

Methods: Over 4,000 young people aged 10–16 years were screened to identify 450 high risk (based on urinary albumin excretion) for a randomised controlled trial (RCT) of statins and ACE inhibitors and 400 low risk subjects for an observational study over 2–4 years.

Results: The results of the RCT, which will be published in 2017 will be reported together with recent analysis of the combined AdDIT cohort of 850 subjects.

Discussion / Conclusion: Implications for early risk stratification and later strategies for prevention of complications will be discussed.

Volume 51

45th Meeting of the British Society for Paediatric Endocrinology and Diabetes

British Society for Paediatric Endocrinology and Diabetes 

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