Endocrine Abstracts

Duloxetine is a serotonin/norepinephrine reuptake inhibitor, prescribed frequently as a first line treatment for Diabetic neuropathy. It is also prescribed for treatment of depression, anxiety disorder and chronic musculoskeletal pain. Hyponatremia is a known adverse effect of most SSRIs including duloxetine and can potentially be life-threatening.Duloxetine induced hyponatremia, however, is relatively rare specially on low doses and is typically seen in the elderly frail pati...

Introduction: Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes, combined together, under the name of MELAS syndrome, constitute one of the mitochondrial genetic diseases with dominant progressive neurodegenerative symptoms. Although nervous system involvement is often the first manifestation of the disease, during the course of the disorder, patient can develop a wide spectrum of endocrine disorders ranging from GH deficiency and hypoparathyroi...