Endocrine Abstracts

Introduction: Graves’ disease (GD) is one of the commonest organ specific autoimmune thyroid disease. Surgical thyroidectomy is one of the definitive treatment modalities. Autoimmunity has been implicated as one of the main cause of GD. In this context, we set out study the role of Pro- inflammatory cytokines in GD.Material and methods: This prospective case-control study was conducted on surgically managed GD patients. Institutional ethical committ...

Resveratrol, a dietary product present in grapes, vegetables, and berries, is phytoestrogen that regulates signaling pathways that control cell division, and growth, apoptosis, and metastasis. Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. Especially, malignant melanoma is pernicious and proliferates more readily than any other skin cancer. In the present study, we evaluated the anti-cancer ...

Background: Immune checkpoint inhibitors (ICI) have become a clinically validated treatment for numerous types of tumor including melanoma, lung, and kidney carcinoma. These treatments can cause immune-related adverse events affecting several organs including the endocrine system.Aims: The aim of this study was to characterize the type and the onset of the ICI associated-endocrinopathies.Materials and methods: This retrospective co...