Endocrine Abstracts

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The skeleton consists of cortical bone and trabecular (cancellous) bone. Cortical bone, which comprises 80% of the skeleton, is designed to provide rigidly and strength and is predominantly found in the long bones, e.g. at the femur. Cancellous bone has a more flexible design with interconnecting trabecles, and is metabolically more active then cortical bone. The balance between formation and resorption is essential for maintaining a normal bone mass and skeletal integrity. Di...

Primary Hyperparathyroidism (PHPT) is the most common disease among parathyroid disorders compared to Chronic Hypoparathyroidism, Calcium Sensor disorders (loss or gain of function mutations) or Parathyroid Cancer. The clinical presentation of PHPT has changed dramatically after the increased accessibility to biochemical analyses. The diagnosis is today often made by change in patients without specific symptoms. Operative treatment is always an option and recommended in patien...