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Endocrine Abstracts (2018) 56 P253 | DOI: 10.1530/endoabs.56.P253

ECE2018 Poster Presentations: Calcium and Bone Calcium & Vitamin D metabolism (59 abstracts)

Tertiary hyperparathyroidism associated with prolactinoma – case report

Cristina Corina Pop-Radu 1,


1University of Medicine and Pharmacy, Targu Mures, Romania; 2Mures County Hospital, Targu Mures, Romania.


Introduction: Tertiary hyperparathyroidism (HPT) occurs most commonly in the setting of renal transplant where patients with secondary HPT continue to have elevated PTH levels after receiving a renal allograft. This disease is observed in up to 30% of kidney transplant recipients. This paper will include a case report and a review of epidemiology and pathophysiology, complications and clinical findings, indications for treatment, and the drugs currently available to treat this condition.

Case report: The 35-years-old woman with a kidney transplant history (2006), subsequently with kidney graft rejection (2014), hemodialysis for 3 years, has addressed to our department in March 2017 for amenorrhea – galactorrhea syndrome (last menstrual cycle 10 years ago). The serum levels of TSH was slightly elevated (8.8 UI/l) with normal FT4, prolactin was 263 ng/ml and FSH, LH, Estradiol, IGF1, basal Cortisol at 8 a.m. were normal. The evaluation of phospho-calcic metabolism emphasized normocalcemia, hyperphosphatemia with elevated intact PTH levels (1050 pg/ml), normal serum levels of 25-hydroxy vitamin D (30 ng/ml) and increased levels of alkaline phosphatase (772 U/L). An ultrasound scan of the neck showed the hyperplasia of three parathyroid glands. 99mTc sestamibi scintigraphy was negative. Bone densitometry (DEXA L1-L4) revealed osteopenia. Pituitary MRI has described a microadenoma. Medical treatment was initiated with Cabergoline and subtotal parathyroidectomy was recommended. Long term follow-up is required for monitoring related complications.

Keywords: tertiary hyperparathyroidism, prolactinoma, subtotal parathyroidectomy.

Volume 56

20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

European Society of Endocrinology 

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