Endocrine Abstracts

Introduction: Graves’ disease is an autoimmune disease, it is considered to be the most common cause of hyperthyroidism. Autoimmune pluriendocrine syndromes include a diverse group of diseases characterized by functional impairment of at least two endocrine glands due to autoimmune events.

Material and methods: This is a retrospective hospital record-based study of patients with Graves’ disease followed up in the day hospital of the department of endocrinology of the CHU Mohamed VI of Marrakech.

Results: A total of 22 patients were analyzed, of which the majority were female, the mean age of presentation in years was 27 years. In addition to Graves‘disease, 9 patients (36.6%) showed other autoimmune disorders: 5 cases of Type 1 diabetes, a case of Sjogren’s syndrome, a case of primary ovarian insufficiency, a case of rheumatoid arthritis and a case of Hodgkin’s lymphoma.

Discussion: Hashimoto’s thyroiditis is often observed together with other autoimmune diseases unlike Graves’ disease; it is an organ-specific autoimmune thyroiditis that can be associated with other non-organ specific autoimmune diseases, which can lead to states of cross-immunity as to widening the range of multiple autoimmune syndromes. Therefore in view of any autoimmune disease, clinical and biological monitoring especially thyroid biological assessment are highly recommended.