Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2019) 63 P10 | DOI: 10.1530/endoabs.63.P10

Hospital Clínico Universitario Virgen de la Victoria, Málaga, Spain.


Introduction: Neuroendocrine tumors are an heterogeneous group of neoplasms with increasing incidence and high survival. The therapies, could be have a negative impact on nutrition and pronogsis of these patients.

Objetives: To analyze analytical and anthropometric parameters in relation to disease stage and survival.

Material and methods: An observational, retrospective and cross-sectional study that includes patients with neuroendocrine tumors. Data are collected at first nutrition appointment in Virgen de la Victoria Clinical Hospital, since 2015 to 2018.

Results: We analyzed data from 42 patients of 59.9±17.6 years of age, 47.6% males; with diagnosis of intestinal neuroendocrine tumor 35.8%, pancreatic 33%, carcinoid 11.9%, gastrinoma 14.3%, other locations 4.8%; Ki67 proliferation index medium 8.9±11.7, stages 1 and 2 95% and non-functioning (73.2%). 36.6% of the patients underwere subjected with pancreatic resection, 29.3% had bowel resection, 2.4% had another type and 31.7% had not surgery, and 28.6% had SSA; SSA + everolimus, QT or imatinib 16.8% and only QT 11.9%. Without treatment 33.3%. No evidence of disease was found in 19%, localized 19% and disseminated 61.9% with a follow-up time of 4.48±4 years. They presented diabetes mellitus previously 23.8%, 14.3% with oral antidiabetics; after diagnosis, increase a 14.3%, treated with ADOs 23.8%, insulin 9.5% and both 4.8%. 43% present steatorrhea, treatment with pancreatin 52.4%, adequate intake 62%; enteral supplements 35.8%, supplements of vitamin D 33.3% and multivitamins 33.3%. Anthropometric parameters: weight 67.4±12.2 kg (decrease of 4.8 Kg compared to usual), BMI 25.1±4.2, MM 48±11 Kg; MG 17.9±7.8 Kg (27±8.8%); AT 35.8±7.2 Kg; IMP 505±109, MB 1373±212 Kcal, AF 5.7±1.2. And analytical: Glucose 102.5±25.8 mg/dl, HbA1c 6.09±1.1, CT 174±51 mg/dl, TG 115±54 mg/dl, Albumin 3.8±0.5 mg/dl, prealbumin 26,2±7.5 mg/dl, vitamin D 26.6±12.2 mg/dl, magnesium 2.2±0.2 mg/dl. In the follow-up there were 4 deaths (9.5%).

Conclusions: Our patients have an acceptable nutritional status, some of them with supplementation. It would be advisable to perform an early screening for an adequate approach.

Volume 63

21st European Congress of Endocrinology

Lyon, France
18 May 2019 - 21 May 2019

European Society of Endocrinology 

Browse other volumes

Article tools

My recent searches

No recent searches.

Authors