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Endocrine Abstracts (2019) 63 P849 | DOI: 10.1530/endoabs.63.P849

1Department of Endocrinology, Diabetology and Metabolic Diseases. UHC Ibn Rochd, Casablanca, Morocco; 2Laboratory of Neuroscience and Mental Health Faculty of Medicine and Pharmacy, Hassan II-Casablanca University, Casablanca, Morocco.


Introduction: Paragangliomas are rare neuroendocrine tumors usually Benign, developed at the expense of sympathetic ganglia, and whose treatment is essentially surgical. We report the case of a patient presenting a cervical paraganglioma hospitalized to the endocrinology department of diabetology and metabolic diseases of Ibn Rochd University Hospital in Casablanca.

Observation: A 57 years old women, not known hypertensive, presenting a mandibular mass evolving since one year, with signs of compression, moreover the patient reported a Triad of Ménard with a slimming quantified to 10 kgs. The examination revealed lateral cervical tumefaction right under mandibular painless fixed 2 cm without lymphadenopathy. Biology has shown an increase in the level of methoxylated derivatives and adrenaline. MRI angiography showed a tissue process of the 4×3.8 cm straight carotid bifurcation arriving in contact with the parotid without separating edge, whereas the MIBG scintigraphy found a right cervical paraganglioma. The patient then underwent a lumpectomy with retrospinal lymph node dissection and the histopathological examination confirmed the diagnosis of cervical paraganglioma without signs of malignancy with reactive adenitis. The evolution was marked by the regression of the MENARD triad and methoxylated control derivatives without anomalies.

Conclusion: Pariangliomas of the head and neck are most commonly developed at the expense of the carotid body and the vagus nerve. The initial assessment is essential to highlight a secreting, multifocal or malignant form, as well as to detect other familial cases. Currently, the standard treatment of these tumors is essentially surgical

Volume 63

21st European Congress of Endocrinology

Lyon, France
18 May 2019 - 21 May 2019

European Society of Endocrinology 

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