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Belgian Endocrine Society 2019

BES 2019

No deleterious effect of pretreatment with everolimus and/or sunitinib on the subacute hematotoxicity of 177Lu-DOTATATE PRRT

ea0064014 | No deleterious effect of pretreatment with everolimus and/or sunitinib on the subacute hematotoxicity of 177Lu-DOTATATE PRRT | BES2019

No deleterious effect of pretreatment with everolimus and/or sunitinib on the subacute hematotoxicity of 177Lu-DOTATATE PRRT

Eva Medaer , Chris Verslype , Cutsem Eric Van , Dekervel Jeroen , Clement Paul , Nackaerts Kristiaan , Bex Marie , Gheysens Olivier , Goffin Karolien , Jentjens Sander , Laere Koen Van , Deroose Christophe M

Background: Treatment of neuro-endocrine tumors (NETs) is often challenging, given the heterogeneity of primary tumor sites, the individual disease complexity and the variety of treatment options. If patients are progressive during first-line treatment with somatostatin analogues (SSA), peptide receptor radionuclide therapy (PRRT) is a validated treatment for somatostatin receptor overexpressing neuroendocrine tumors. The NETTER-1 trial has demonstrated a pronounced positive e...