Endocrine Abstracts

Acromegaly is a chronic disease caused almost invariably by a pituitary GH-secreting adenoma leading to overproduction of insulin-like growth factor I (IGF-I). The long-term hypersecretion leads to many comorbidities, as diabetes mellitus, arterial hypertension, and cardiovascular and/or pulmonary disease (including sleep apnea), which are related to an increased mortality rate. In fact, uncontrolled acromegaly is associated with a three times mortality rate as compared with n...

In December 2019, the outbreak of coronavirus disease (COVID-19) started in Wuhan, China1, resulting in a global pandemic. A novel coronavirus (SARS-CoV-2) was identified. The virus enters the pneumocyte through the angiotensin-converting enzyme 2 (ACE2) as a receptor2. The enzyme is widely expressed. A relationship between COVID-19 and the endocrine system occurs at multiple levels. On autopsies, infarct, edema, and neuronal degeneration with SARS-CoV ge...

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