SFEBES2022 Poster Presentations Adrenal and Cardiovascular (66 abstracts)
Sulfasalazine as a cause of false positive elevation of normetanephrine in patients with adrenal mass – A diagnostic challenge
Eunice Ter Zuling & Sabapathy Balasubramanian
Northern General Hospital, Sheffield, United Kingdom
In clinical settings, when biochemical screening revealed grossly elevated urinary normetanephrine and metanephrine in the presence of an adrenal mass, there is a high clinical suspicion of a pheochromocytoma. However, sulfasalazine, an anti-inflammatory drug can cause analytical drug interference, leading to falsely positive elevation of urinary normetanephrine and a misdiagnosis of phantom pheochromocytoma. This report illustrates two patients with adrenal mass who had false positive elevation of normetanephrine due to sulfasalazine, one of whom underwent adrenalectomy and another one did not.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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