Hirsutism and anthropometric parameters in obese Tunisian women: A correlation study

Chayma Bel Hadj Sliman; Amor Nadia Ben; Faten Mahjoub; Berriche Olfa; Khaoula Ben Ali; Othman Rym Ben; Ramla Mizouri; Gammoudi Amel; Kacem Awatef; Jamoussi Henda

doi:10.1530/endoabs.90.EP558

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Endocrine Abstracts (2023) 90 EP558 | DOI: 10.1530/endoabs.90.EP558

ECE2023 Eposter Presentations Diabetes, Obesity, Metabolism and Nutrition (355 abstracts)

Hirsutism and anthropometric parameters in obese Tunisian women: A correlation study

Bel Hadj Sliman Chayma , Nadia Ben Amor , Faten Mahjoub , Berriche Olfa , Ben Ali Khaoula , Rym Ben Othman , Ramla Mizouri , Gammoudi Amel , Kacem Awatef & Jamoussi Henda

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National Institute of Nutrition, Service A of Diabetology and Nutrition, Tunis, Tunisia

Introduction: Hirsutism is a common disorder that occurs in 5% to 10% of women of reproductive age. The aim of this study is to evaluate the relation between anthropometric parameters (AP) and hirsutism in Tunisian obese woman.

Methods: A descriptive cross-sectional study was conducted at the obesity unit of the national institute of nutrition of Tunis including 65 obese women of reproductive age. data were collected by questioning, examining the patient and from medical records. The Ferriman-Gallwey score was used to evaluate hirsutism. Hirsutism was defined by a score higher than eight. Our population was divided into 2 groups: 26 hirsute women (H+) and 39 healthy women as a control group (H−). The AP considered were: weight, body mass index (BMI), waist circumference (WC) and body fat percentage (BFP). Testosteronemia was measured in hirsute women.

Results: The mean age of patients was 33.3±10.8 years. Menstrual disorders were reported in 32.3% of cases. Morbid obesity was found in 34.9% of cases. Significantly higher differences between H+ and H− groups were shown regarding mean weight (107.3±25.5 versus 93.6±14.7 kg; P=0.005), mean BMI (40.5±8.4 kg/m² versus 35.4±5.5 kg/m²; P=0.008), WC (121.3±17.1 cm versus 107.2±11.7 cm; P=0.005) and BFP (48.2±7.1% versus 44.3±4.6%; P=0.03). A BMI above 36.9 kg/m² (OR=5.4; P=0.004), a WC above 109 cm (OR=9.3; P=0.004) and a BFP above 109 cm (OR=6.9; P=0.005) were significantly associated with the presence of hirsutism. In hirsute women, The mean blood testosterone level was 0.3±0.2 ng/ml and there was a correlation between Testosteronemia and Weight (P=0.019).

Conclusion: Our study clearly shows that hirsute women had higher AP. In fact, adipose tissue is implicated in the production of androgens. Therefore, weight loss of obese and overweight is strongly recommended.