ECEESPE2025 ePoster Presentations Adrenal and Cardiovascular Endocrinology (170 abstracts)
Ectopic secretion of ACTH: diagnosis and management a case report
Rania Dassoufi 1 , Oussama Jaddi 1 , Sana Rafi 1 , Ghizlane El Mghari 1 & Nawal El Ansari 1
1Mohamed 6 University Hospital of Marrakech, Endocrinology-Metabolic Diseases-Nutrition Department, Marrakech, Morocco
JOINT831
Introduction: Cushing’s syndrome (CS) is the set of symptoms associated with hypercorticism, the ectopic origin of ACTH, is more expressive and can be caused by a variety of tumours. We report this case in order to highlight this special features.
Case report: 33 year old female with frank clinical and biological AXTH dependent cushing’s syndrome, with normal pituitary MRI and adrenal CT scan. An octreoscan was performed, showing a thyroid and lymphonodal lesions suggesting ectopic secretion of ACTH. We proposed symptomatic treatment with ketoconazole followed by appropriate surgical management, with a good improvement after surgery.
Discussion: Ectopic ACTH secretion is a rare cause of hypercorticism, and octreoscann is a major diagnostic tool. Surgery combined with symptomatic treatment represents the essence of treatment.
Conclusion: ACTH-dependent cushing’s syndrome with ectopic secretion remains a very rare entity that can be difficult to diagnose and manage.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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