ECEESPE2025 ePoster Presentations Diabetes and Insulin (245 abstracts)
Can we predict the onset or worsening of microangiopathies in pregnant women with diabetes mellitus during pregnancy?
Hadhemi Belhassen 1 , Yosra Htira 1 , Chaima Jemai 1 , Laajili Olfa 1 , Hedfi Imene 1 , Haj Ali Zohra 1 & Feika Ben Mami 1
1National Institute of Nutrition, C, Tunis, Tunisia
JOINT3753
Introduction: Pregnancy is a major factor in the imbalance of diabetes, irrespective of its type. It favours the onset and/or worsening of microvascular complications such as diabetic retinopathy and nephropathy. Our study aims to highlight potential predisposing factors to these microangiopathies in diabetic pregnant women.
Methods: We conducted a descriptive retrospective study involving 100 known diabetic pregnant women in ward C of the National Institute of Nutrition.
Results: The mean age was 32.87± 5.3 years, with a predominance of multigestational women (54%) and nulliparous women (37%). Type 2 diabetes was present in 52% of parturients. The average duration of diabetes for all types was 7.57 ± 6.66 years. A minority (29%) had well-controlled diabetes on treatment, with an HbA1C<7%. Non-proliferative diabetic retinopathy and diabetic nephropathy associated with at least one microalbuminuria complicated 6.1% and 4.8% of diabetics, respectively. No new onset or worsening of diabetic retinopathy was detected throughout the pregnancy. The same applies to the worsening of diabetic nephropathy and creatinine clearance. The only patient with macroalbuminuria decreased her proteinuria during pregnancy.
Conclusions: Glycaemic and blood pressure control are protective factors against microangiopathies during pregnancy, even in cases of previously complicated diabetes. Hence, the importance of pregnancy planning and monitoring during the gestational period.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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