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Endocrine Abstracts (2025) 110 EP584 | DOI: 10.1530/endoabs.110.EP584

1Central Hospital of Army Algiers, Algiers, Algeria


JOINT936

Introduction: Papillary thyroid cancer rarely affects children. More aggressive in form, it is often metastatic upon diagnosis; these metastases most often concern cervical adenopathies and the lung. Its prognosis remains excellent because metastases generally respond well to surgery and treatment with radioactive iodine.

Material and method: This is a retrospective study of 13 patients followed up at our facility between 2003 and 2024. A total of 13 children, sex ratio 2.25 girls, average age 14.84 years [5-18 years], one child had a history of cervical irradiation for lymphoma. All children had undergone total thyroidectomy with at least central lymph node dissection. Tumor size 21.11 mm vascular emboli, thyroid invasion and extrathyroidal invasion were noted in half of the patients. 8 patients had metastatic adenopathies, 5 of them pulmonary metastases and one patient a cranial metastasis revealing her thyroid microcarcinoma. The average iodine activity received was 300mci [30-900mci], unfortunately one patient had as a side effect the development of primary ovarian insufficiency. Currently, 9 patients are in remission, lesion stability is noted in 3 of them and one patient is lost to follow-up.

Discussion/Conclusion: The occurrence of papillary thyroid carcinoma in children is a source of anxiety for those around them and for the doctor. However, early diagnosis, as well as intensive management, most often allow stability and cure.

Volume 110

Joint Congress of the European Society for Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE) 2025: Connecting Endocrinology Across the Life Course

European Society of Endocrinology 
European Society for Paediatric Endocrinology 

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