Endocrine Abstracts

JOINT2023

Objectives: To study the epidemiological, clinical, anatomopathological, and therapeutic particularities of follicular thyroid carcinoma (FTC).

Patients and Methods: This is a retrospective study involving 20 patients treated for FTC over a period of 14 years.

Results: The average age was 49 years, with a female-to-male ratio of 5.66. The mode of discovery was a cervical mass in 17 cases, bone metastasis in 2 cases, and compression signs in 1 case. The average consultation delay was 16 months. Cervical ultrasound performed in all cases revealed thyroid nodules classified as EUTIRADS 3 (80%), EUTIRADS 4 (15%), and EUTIRADS 5 (5%). Fine needle aspiration was performed in 3 patients (15%). Surgery involved thyroid surgery in all cases, with central node dissection in 12 cases (60%) and selective lateral dissection in 1 case (5%). The frozen section examination was conducted for all patients, with benign results in 15 cases (75%) and malignant results in 5 cases (25%). Definitive histological examination confirmed the diagnosis of FTC in all cases. Staging for recurrence risk categorized the patients into 3 groups: low risk in 15 cases, intermediate risk in 1 case, and high risk in 4 cases. Ninety-five percent of patients received radioactive iodine therapy. Whole-body scanning revealed pulmonary metastases in 2 cases and bone metastasis in 2 cases. The average follow-up duration was 49.7 months.

Conclusion: FTC represents 10-15% of all thyroid carcinomas. It tends to metastasize more frequently to distant sites, particularly to the lungs and bones.