ECEESPE2025 ePoster Presentations Endocrine Related Cancer (100 abstracts)
Thyroid metastasis of pulmonary choriocarcinoma: a rare and challenging diagnosis
Jaweher Kechiche 1 , Abir Meherzi 1 , Taieb Ach 2 , Habiba Ben Sghaier 1 , Mouna Bellakhdher 1 , Jihen Houas 1 , Malika El Omri 1 , Ghada Saad 2 , Monia Ghammem 1 , Yosra Hasni El Abed 2 , Wassin Kermani 1 & Mohamed Abdelkefi 1
1Farhat Hached University Hospital, ENT Head and Neck Surgery, Sousse, Tunisia; 2Farhat Hached University Hospital, Endocrinology Departement, Sousse, Tunisia
JOINT3880
Introduction: Metastatic disease to the thyroid is an uncommon but welldocumented event and accounts for 1–9 % of all thyroid malignancies. The three most common neoplasms to metastasize to the thyroid were from the kidney, lung, gastrointestinal tract and breast, respectively. The treatment options in patients with metastatic disease to the thyroid gland should be made based upon the condition of the patient, extent of the disease, stage, and volume The aim of this report is to present this case and discuss the diagnostic difficulties of an unusual presentations of thyroid metastasis of choriocarcinoma
Materiel and methods: We report a rare case of thyroid metastasis from lung choriocarcinoma.
Observation: A 55 year-old male patient, with a history of Hodgkin’s lymphoma treated with radiochemotherapy in 1998, complained of a cervical mass for 4 month. He was referred for exploration and management of the mass. On examination, a 10-cm growth was palpable on the right paramedian anterior neck, in favour of a heterogenous thyroid goiter. β -hCG was elevated. CT scan showed a suspicious excavated mass in the posteroinferior segment of the left inferior lobe of the lung, along with solid nodules and confluent mediastinal and hilar enlarged nodes. Cervical lymphadenopathies, adrenal and cerebral nodules indicative of metastasis, were also observed, and heterogeneous thyroid goiter. A primary pulmonary malignancy was suspected. Fine needle aspiration showed anaplastic malignant cellsA thyroid biopsy was performed, indicating the presence of trophoblastic cells characteristic of a choriocarcinoma metastasis in the thyroid gland. These findings were corroborated by the presence of the same malignant cells in the bronchial biopsy. β -hCG was elevated. The multidisciplinary team decision was to start chemotherapy. Unfortunately, the patient passed away before he could be started on chemotherapy.
Conclusions: Metastasis to the thyroid gland is a rare condition that may pose a diagnostic challenge. the overall prognosis is poor.
Volume 110
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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