ECEESPE2025 ePoster Presentations Endocrine Related Cancer (100 abstracts)
Risk factors and malnutrition in colorectal cancer patients: identification and clinical implications
Rezgui Mohamed Amine 1 , Rym Ben Othman 1 , Ramla Mizouri 1 , Berriche Olfa 1 , Rachdi Rim 1 , Jamoussi Henda 1 , Mahjoub Faten 1 , Belguith Jihed 1 & Mansour Sabrine 1
1National Institute of Nutrition and Food Technologies, Tunisia
JOINT2968
Introduction: Colorectal cancer (CRC) is a public health problem. The aim of this study is to determine the relationship between nutritional and environmental risk factors and the onset of CRC.
Methods: This was a retrospective study conducted among 50 CRC patients recruited from the gastroenterology and surgery departments of La Rabta Hospital in Tunisia, as well as 50 randomly selected controls. The two groups were matched for age and gender. A questionnaire was used to collect data on personal and family medical history, clinical data regarding CRC and its treatment, as well as anthropometric measurements and biological tests. A frequency questionnaire and a 24-hour recall were performed.
Results: There was a female predominance among our patients (n= 26, 52%). The age of the patients ranged from 29 to 84 years, with a mean of 56.06 ± 14.24 years. Tobacco and alcohol consumption were higher among patients than controls, but this difference was not statistically significant (P = 0.1 and P = 0.18, respectively). Significant risk factors included obesity (P = 0.02), menopause (P = 0.006), as well as high consumption of red meat (P = 0.002), processed meat (P = 0.002), fried foods (P = 0.0001), and sugar (P = 0.0001). Consumption of green tea (P = 0.003), fruits (P = 0.001), and cereals (P = 0.0001) was higher among controls. Anorexia was nearly constant. Malnutrition was common, measured by BMI, percentage of weight loss (42%), albumin levels (60%), and various nutritional scores (NRI, MUST, MNA, and SGA). Energy and protein intake were below recommended needs for 94% and 92% of patients, respectively. Deficiencies in minerals, vitamins, and trace elements were observed.
Conclusion: A sedentary lifestyle and inappropriate dietary choices were higher in CRC group. Malnutrition was frequent in cancer patients. We suggest a screening for malnutrition in all CRC patients.
Volume 110
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Endocrine Abstracts
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